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- W71664564 abstract "Nephron function is segmented. Each segment has characteristic transport mechanisms and individual eicosanoid profiles [1,[2]]. Mapping the distribution of AA metabolizing enzymes within the nephron is essential to understanding the contribution of eicosanoids to excretory function. The study of Bonvalet et al addressed the localization of cyclooxygenase (COX) in the nephron and uncovered large segments that had negligible COX activity, particularly the proximal tubules (PT) and the thick ascending limb (TAL) [[3]], which later studies identified as segments heavily invested with cytochrome monooxygenase (CYP450) activity [[4],[5]]." @default.
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- W71664564 date "2003-01-01" @default.
- W71664564 modified "2023-09-27" @default.
- W71664564 title "Cytochrome P450 Arachidonic Acid Metabolites Modulate Renal Tubular Function" @default.
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- W71664564 doi "https://doi.org/10.1007/978-1-4419-9194-2_13" @default.
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