Matches in SemOpenAlex for { <https://semopenalex.org/work/W71742283> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W71742283 abstract "In irradiated animals, Cu and Co increase in the blood and in many organs, apparently withdrawn from the liver depots. This may be considered a protective mechanism. In the irradiated animal, highly toxic substances, free radicals, and peroxides, form and accumulate in the organism, resulting in a series of reactions in the animal. In the healthy organism the presence of natural antioxidants prevents such accumulation. When the oxygen content of the tissue is low, radical formation is less; the decrease in tissue respiration creates a tissue hypoxia, protecting the organism from radiation damage. Oxygen in the tissue is decreased by Cu, respiratory enzymes are suppressed, and hypoxia results. Histaminase activity is decreased, and the resulting increase in histamine increases the capillary wall permeability to plasma, edema results, oxygen supply to the tissue is interferred with, and hypoxia occurs. The hyaluronidase activity is also increased, with increased vessel permeability, hemorrhagic effects, lowering of the connective tissue barrier effects, and spread of toxic substances to the tissues. Tyrosinase activity is decreased, with formation of adrenalin. Morphological changes occur in various tissues. Fe is lowered in the liver, shortening erythrocyte life and decreasing antitoxic properties of lymph. The Co increase in the tissuesmore » lowers the hemoglobin capacity for oxygen, with resulting tissue hypoxia, increases catalase activity and causes other changes. Co combines with methionine, nicotinic acid, vitamins B-1 and B-12, but suppresses erythropoiesis and interferes with synthesis of RNA, cysteine, and choline and therefore disturbs phospholipid formation in the liver. (29 references) (TTT)« less" @default.
- W71742283 created "2016-06-24" @default.
- W71742283 creator A5048387148 @default.
- W71742283 date "1963-01-01" @default.
- W71742283 modified "2023-09-26" @default.
- W71742283 title "THE IMPORTANCE OF CERTAIN TRACE ELEMENTS IN THE DEVELOPMENT OF RADIATION PATHOLOGY" @default.
- W71742283 hasPublicationYear "1963" @default.
- W71742283 type Work @default.
- W71742283 sameAs 71742283 @default.
- W71742283 citedByCount "0" @default.
- W71742283 crossrefType "journal-article" @default.
- W71742283 hasAuthorship W71742283A5048387148 @default.
- W71742283 hasConcept C1122143 @default.
- W71742283 hasConcept C126322002 @default.
- W71742283 hasConcept C134018914 @default.
- W71742283 hasConcept C178790620 @default.
- W71742283 hasConcept C185592680 @default.
- W71742283 hasConcept C2778004101 @default.
- W71742283 hasConcept C2778248108 @default.
- W71742283 hasConcept C2778917026 @default.
- W71742283 hasConcept C2778979269 @default.
- W71742283 hasConcept C2779703530 @default.
- W71742283 hasConcept C518705261 @default.
- W71742283 hasConcept C540031477 @default.
- W71742283 hasConcept C54355233 @default.
- W71742283 hasConcept C55493867 @default.
- W71742283 hasConcept C71924100 @default.
- W71742283 hasConcept C7836513 @default.
- W71742283 hasConcept C86803240 @default.
- W71742283 hasConceptScore W71742283C1122143 @default.
- W71742283 hasConceptScore W71742283C126322002 @default.
- W71742283 hasConceptScore W71742283C134018914 @default.
- W71742283 hasConceptScore W71742283C178790620 @default.
- W71742283 hasConceptScore W71742283C185592680 @default.
- W71742283 hasConceptScore W71742283C2778004101 @default.
- W71742283 hasConceptScore W71742283C2778248108 @default.
- W71742283 hasConceptScore W71742283C2778917026 @default.
- W71742283 hasConceptScore W71742283C2778979269 @default.
- W71742283 hasConceptScore W71742283C2779703530 @default.
- W71742283 hasConceptScore W71742283C518705261 @default.
- W71742283 hasConceptScore W71742283C540031477 @default.
- W71742283 hasConceptScore W71742283C54355233 @default.
- W71742283 hasConceptScore W71742283C55493867 @default.
- W71742283 hasConceptScore W71742283C71924100 @default.
- W71742283 hasConceptScore W71742283C7836513 @default.
- W71742283 hasConceptScore W71742283C86803240 @default.
- W71742283 hasLocation W717422831 @default.
- W71742283 hasOpenAccess W71742283 @default.
- W71742283 hasPrimaryLocation W717422831 @default.
- W71742283 hasRelatedWork W1512456078 @default.
- W71742283 hasRelatedWork W1769032952 @default.
- W71742283 hasRelatedWork W1816424375 @default.
- W71742283 hasRelatedWork W1977618605 @default.
- W71742283 hasRelatedWork W1986853155 @default.
- W71742283 hasRelatedWork W2040619550 @default.
- W71742283 hasRelatedWork W2065134263 @default.
- W71742283 hasRelatedWork W2074026943 @default.
- W71742283 hasRelatedWork W2077719038 @default.
- W71742283 hasRelatedWork W2123582374 @default.
- W71742283 hasRelatedWork W2404157610 @default.
- W71742283 hasRelatedWork W2413845936 @default.
- W71742283 hasRelatedWork W2418953504 @default.
- W71742283 hasRelatedWork W2419552232 @default.
- W71742283 hasRelatedWork W2460431179 @default.
- W71742283 hasRelatedWork W2582358573 @default.
- W71742283 hasRelatedWork W2994239096 @default.
- W71742283 hasRelatedWork W30926683 @default.
- W71742283 hasRelatedWork W64840984 @default.
- W71742283 hasRelatedWork W1578693528 @default.
- W71742283 isParatext "false" @default.
- W71742283 isRetracted "false" @default.
- W71742283 magId "71742283" @default.
- W71742283 workType "article" @default.