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- W71761651 abstract "Old subjects exhibit a progressive modification in the distribution of lymphocyte subpopulations present in the peripheral blood, an impaired proliferative response to mitogens and a decreased NK cytotoxicity. In this study we analyzed the lytic activity of clones with different phenotype derived from the peripheral blood lymphocytes of elderly and young subjects. CD8+ clones from old subjects presented a decreased lytic activity against K562 and P815-IgG target lines, confirming that cytotoxicity is also impaired when tested at clonal level." @default.
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- W71761651 date "1987-01-01" @default.
- W71761651 modified "2023-09-26" @default.
- W71761651 title "CYTOTOXIC ACTIVITY OF LYMPHOCYTE CLONES FROM AGED PEOPLE" @default.
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- W71761651 doi "https://doi.org/10.1016/b978-0-08-035588-7.50045-5" @default.
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