Matches in SemOpenAlex for { <https://semopenalex.org/work/W720876> ?p ?o ?g. }
- W720876 endingPage "79" @default.
- W720876 startingPage "1369" @default.
- W720876 abstract "Elderly Hodgkin lymphoma (HL), commonly defined as occuring in patients over 60 to 65 years of age, is an uncommon disease. In population-based studies, the proportion of HL patients over age 60 years has rangedfrom 15% to 30%. However, the proportion of patients over age 60 years in clinical trials has been considerably lower, typically constituting < 5% to 10% of participants. Elderly HL patients commonly present with mixed cellularity histology, B symptoms, advanced stage, and Epstein-Barr virus-positive disease. Progression-free and overall survival rates for elderly HL patients are disproportionately inferior to those of younger patients. Generally, treatment of elderly HL for all disease stages should be given with curative intent, but more effective, tolerable therapeutic regimens are needed. No standard treatment recommendations exist for elderly HL Bleomycin-containing regimens including ABVD (doxorubicin [Adriamycin], bleomycin, vinblastine, dacarbazine) are associated with pulmonary toxicity, and intensive therapy such as BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine [Oncovin], procarbazine [Matulane], prednisone) is poorly tolerated, whereas less-intensive regimens such as CVP/CEB (chlorambucil [Leukeran], vinblastine, procarbazine, prednisone, cyclophosphamide, etoposide, bleomycin) and ChlVPP (chlorambucil, vinblastine, procarbazine, prednisolone) appear to be less effective than anthracycline-based regimens. Recent data using CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) in this population merit further investigation. In addition, further evaluation of the prognostic value of early PET in elderly HL is warranted. Continued multicenter collaborations with prospective clinical trials, including formal assessment of comorbidity and functional status, will be critical to the successful study of elderly HL." @default.
- W720876 created "2016-06-24" @default.
- W720876 creator A5029655862 @default.
- W720876 creator A5064091455 @default.
- W720876 creator A5072154632 @default.
- W720876 date "2008-11-15" @default.
- W720876 modified "2023-09-23" @default.
- W720876 title "Hodgkin lymphoma in older patients: an uncommon disease in need of study." @default.
- W720876 cites W139456487 @default.
- W720876 cites W1533031882 @default.
- W720876 cites W1773679988 @default.
- W720876 cites W1775377720 @default.
- W720876 cites W1880639950 @default.
- W720876 cites W1970129186 @default.
- W720876 cites W1974028805 @default.
- W720876 cites W1988585909 @default.
- W720876 cites W1989577949 @default.
- W720876 cites W2006391862 @default.
- W720876 cites W2010746974 @default.
- W720876 cites W2012324903 @default.
- W720876 cites W2027293043 @default.
- W720876 cites W2027296497 @default.
- W720876 cites W2031593269 @default.
- W720876 cites W2032870251 @default.
- W720876 cites W2034030408 @default.
- W720876 cites W2036583226 @default.
- W720876 cites W2040610061 @default.
- W720876 cites W2042121530 @default.
- W720876 cites W2046245147 @default.
- W720876 cites W2046667779 @default.
- W720876 cites W2050942542 @default.
- W720876 cites W2053467648 @default.
- W720876 cites W2054878443 @default.
- W720876 cites W2056072361 @default.
- W720876 cites W2058015212 @default.
- W720876 cites W2072430038 @default.
- W720876 cites W2076334524 @default.
- W720876 cites W2080080520 @default.
- W720876 cites W2087307665 @default.
- W720876 cites W2087989353 @default.
- W720876 cites W2092721029 @default.
- W720876 cites W2094431983 @default.
- W720876 cites W2099297962 @default.
- W720876 cites W2105259666 @default.
- W720876 cites W2109633064 @default.
- W720876 cites W2110635832 @default.
- W720876 cites W2116258174 @default.
- W720876 cites W2119706387 @default.
- W720876 cites W2131636403 @default.
- W720876 cites W2140283409 @default.
- W720876 cites W2141615510 @default.
- W720876 cites W2141686677 @default.
- W720876 cites W2147040815 @default.
- W720876 cites W2148999297 @default.
- W720876 cites W2149430422 @default.
- W720876 cites W2150456018 @default.
- W720876 cites W2156636734 @default.
- W720876 cites W2157851009 @default.
- W720876 cites W2161762488 @default.
- W720876 cites W2163066856 @default.
- W720876 cites W2164925653 @default.
- W720876 cites W2165308914 @default.
- W720876 cites W2168398638 @default.
- W720876 cites W2171255046 @default.
- W720876 cites W2273821312 @default.
- W720876 cites W2283975110 @default.
- W720876 cites W2328676772 @default.
- W720876 cites W74083053 @default.
- W720876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19086599" @default.
- W720876 hasPublicationYear "2008" @default.
- W720876 type Work @default.
- W720876 sameAs 720876 @default.
- W720876 citedByCount "13" @default.
- W720876 countsByYear W7208762012 @default.
- W720876 countsByYear W7208762014 @default.
- W720876 countsByYear W7208762015 @default.
- W720876 countsByYear W7208762016 @default.
- W720876 countsByYear W7208762019 @default.
- W720876 countsByYear W7208762020 @default.
- W720876 countsByYear W7208762022 @default.
- W720876 crossrefType "journal-article" @default.
- W720876 hasAuthorship W720876A5029655862 @default.
- W720876 hasAuthorship W720876A5064091455 @default.
- W720876 hasAuthorship W720876A5072154632 @default.
- W720876 hasConcept C126322002 @default.
- W720876 hasConcept C141071460 @default.
- W720876 hasConcept C143998085 @default.
- W720876 hasConcept C2776305933 @default.
- W720876 hasConcept C2776694085 @default.
- W720876 hasConcept C2776755627 @default.
- W720876 hasConcept C2777132456 @default.
- W720876 hasConcept C2777866208 @default.
- W720876 hasConcept C2779112685 @default.
- W720876 hasConcept C2779429289 @default.
- W720876 hasConcept C2780964509 @default.
- W720876 hasConcept C2908647359 @default.
- W720876 hasConcept C71924100 @default.
- W720876 hasConcept C99454951 @default.