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- W72100183 abstract "Argiris Efstratiadis Department of Biological Chemistry Harvard Medical School Boston, Massachusetts 02115 James W. Posakony, Tom Maniatis, Richard M. Lawn* and Catherine O’Connell+ Division of Biology California Institute of Technology Pasadena, California 91125 Richard A. Spritz, Jon K. DeRiel,# Bernard G. Forget and Sherman M. Weissman Departments of Genetics and Internal Medicine Yale University School of Medicine New Haven, Connecticut 06510 Jerry L. Slightom, Ann E. Blechl and Oliver Smithies Laboratory of Genetics University of Wisconsin Madison, Wisconsin 53706 Francisco E. Baralle, Carol C. Shoulders and Nicholas J. ProudfootQ MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH, England Summary We present the results of a detailed comparison of the primary structure of human p-like globin genes and their flanking sequences. Among the se- quences located 5’ to these genes are two highly conserved regions which include the sequences ATA and CCAAT located 31 2 1 and 77 + 10 bp, respectively, 5’ to the mRNA capping site. Similar sequences are found in the corresponding locations in most other eucaryotic structural genes. Calcula- tion of the divergence times of individual @like globin gene pairs provides the first description of the evolutionary relationships within a gene family based entirely on direct nucleotide sequence com- parisons. In addition, the evolutionary relationship of the embryonic e-globin gene to the other human P-like globin genes is defined for the first time. Finally, we describe a model for the involvement of short direct repeat sequences in the generation of deletions in the noncoding and coding regions of B-like globin genes during evolution." @default.
- W72100183 created "2016-06-24" @default.
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- W72100183 date "1980-01-01" @default.
- W72100183 modified "2023-09-24" @default.
- W72100183 title "The Structure and Evolution of the Human /?-Globin Gene Family" @default.
- W72100183 cites W114651734 @default.
- W72100183 cites W1540318286 @default.
- W72100183 cites W1602899744 @default.
- W72100183 cites W160629171 @default.
- W72100183 cites W1877124491 @default.
- W72100183 cites W1963762473 @default.
- W72100183 cites W1964344173 @default.
- W72100183 cites W1964464684 @default.
- W72100183 cites W1964592653 @default.
- W72100183 cites W1964674348 @default.
- W72100183 cites W1965585699 @default.
- W72100183 cites W1967318154 @default.
- W72100183 cites W1968647996 @default.
- W72100183 cites W1968697334 @default.
- W72100183 cites W1968882642 @default.
- W72100183 cites W1970562650 @default.
- W72100183 cites W1970977612 @default.
- W72100183 cites W1973455868 @default.
- W72100183 cites W1975307779 @default.
- W72100183 cites W1977728729 @default.
- W72100183 cites W1982225512 @default.
- W72100183 cites W1982610079 @default.
- W72100183 cites W1982666619 @default.
- W72100183 cites W1984220134 @default.
- W72100183 cites W1988484106 @default.
- W72100183 cites W1996507241 @default.
- W72100183 cites W1997529213 @default.
- W72100183 cites W2001337273 @default.
- W72100183 cites W2006997428 @default.
- W72100183 cites W2007230848 @default.
- W72100183 cites W2008265915 @default.
- W72100183 cites W2013946016 @default.
- W72100183 cites W2016240281 @default.
- W72100183 cites W2017118249 @default.
- W72100183 cites W2018205338 @default.
- W72100183 cites W2018972218 @default.
- W72100183 cites W2019654058 @default.
- W72100183 cites W2021889598 @default.
- W72100183 cites W2023466209 @default.
- W72100183 cites W2024457805 @default.
- W72100183 cites W2027411626 @default.
- W72100183 cites W2028525826 @default.
- W72100183 cites W2029544166 @default.
- W72100183 cites W2029777385 @default.
- W72100183 cites W2029800274 @default.
- W72100183 cites W2033967078 @default.
- W72100183 cites W2035591204 @default.
- W72100183 cites W2042586851 @default.
- W72100183 cites W2043430985 @default.
- W72100183 cites W2044648543 @default.
- W72100183 cites W2045196584 @default.
- W72100183 cites W2045230343 @default.
- W72100183 cites W2048137516 @default.
- W72100183 cites W2049905397 @default.
- W72100183 cites W2052276649 @default.
- W72100183 cites W2054684040 @default.
- W72100183 cites W2058689603 @default.
- W72100183 cites W2060693949 @default.
- W72100183 cites W2063921293 @default.
- W72100183 cites W2063954951 @default.
- W72100183 cites W2067605519 @default.
- W72100183 cites W2068609723 @default.
- W72100183 cites W2069148911 @default.
- W72100183 cites W2069526940 @default.
- W72100183 cites W2079323437 @default.
- W72100183 cites W2080131469 @default.
- W72100183 cites W2080209412 @default.
- W72100183 cites W2083070222 @default.
- W72100183 cites W2083420802 @default.
- W72100183 cites W2087062536 @default.
- W72100183 cites W2087626594 @default.
- W72100183 cites W2092105551 @default.
- W72100183 cites W2108785509 @default.
- W72100183 cites W2114624600 @default.
- W72100183 cites W2121490064 @default.
- W72100183 cites W2144471538 @default.
- W72100183 cites W2147722148 @default.
- W72100183 cites W2164269528 @default.
- W72100183 cites W2172275455 @default.
- W72100183 cites W2322672979 @default.
- W72100183 cites W2323950828 @default.