Matches in SemOpenAlex for { <https://semopenalex.org/work/W72436669> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W72436669 endingPage "9" @default.
- W72436669 startingPage "1384" @default.
- W72436669 abstract "To investigate the serum levels of insulin-like growth factor-I (IGF-I) in patients with fibromyalgia (FM) compared to healthy controls and patients with other rheumatic diseases, and to explore possible etiologic mechanisms of low IGF-I levels in patients with FM.Five hundred patients with FM and 152 controls (74 healthy blood donors, 26 myofascial pain patients and 52 patients with other rheumatic diseases) were studied. All had measurements of acid extracted serum IGF-I. A subset of 90 patients with FM were evaluated for clinical features that might explain low IGF-I levels. Twenty-five patients with FM underwent growth hormone (GH) provocation testing with l-dopa and clonidine.The mean serum IGF-I level in patients with FM was 138 +/- 56 ng/ml and in controls 215 +/- 86 ng/ml (p = 0.00000000001). Low levels of IGF-I were not due to depression, tricyclic medications, nonsteroidal antiinflammatory drugs, poor aerobic conditioning, obesity, or pain level. Patients with focal myofascial pain syndromes had normal IGF-I levels (236 +/- 68), as did most patients with other rheumatic disorders, unless they had concomitant FM. Patients with FM with initially normal levels often had a rapid decline of IGF-I over 1 to 2 years. Most patients with FM with low IGF-I levels failed to secrete GH after stimulation with clonidine and l-dopa.Many, but not all, patients with FM have low levels of IGF-I that cannot be explained by clinical associations. These results suggest that low IGF-I levels in patients with FM are a secondary phenomenon due to hypothalamic-pituitary-GH axis dysfunction." @default.
- W72436669 created "2016-06-24" @default.
- W72436669 creator A5006713627 @default.
- W72436669 creator A5010513682 @default.
- W72436669 creator A5046462973 @default.
- W72436669 creator A5054759847 @default.
- W72436669 creator A5058683952 @default.
- W72436669 date "1997-07-01" @default.
- W72436669 modified "2023-09-29" @default.
- W72436669 title "Hypothalamic-pituitary-insulin-like growth factor-I axis dysfunction in patients with fibromyalgia." @default.
- W72436669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9228141" @default.
- W72436669 hasPublicationYear "1997" @default.
- W72436669 type Work @default.
- W72436669 sameAs 72436669 @default.
- W72436669 citedByCount "74" @default.
- W72436669 countsByYear W724366692012 @default.
- W72436669 countsByYear W724366692013 @default.
- W72436669 countsByYear W724366692014 @default.
- W72436669 countsByYear W724366692015 @default.
- W72436669 countsByYear W724366692017 @default.
- W72436669 countsByYear W724366692021 @default.
- W72436669 countsByYear W724366692022 @default.
- W72436669 countsByYear W724366692023 @default.
- W72436669 crossrefType "journal-article" @default.
- W72436669 hasAuthorship W72436669A5006713627 @default.
- W72436669 hasAuthorship W72436669A5010513682 @default.
- W72436669 hasAuthorship W72436669A5046462973 @default.
- W72436669 hasAuthorship W72436669A5054759847 @default.
- W72436669 hasAuthorship W72436669A5058683952 @default.
- W72436669 hasConcept C110586980 @default.
- W72436669 hasConcept C126322002 @default.
- W72436669 hasConcept C134018914 @default.
- W72436669 hasConcept C139719470 @default.
- W72436669 hasConcept C142724271 @default.
- W72436669 hasConcept C162324750 @default.
- W72436669 hasConcept C170493617 @default.
- W72436669 hasConcept C204787440 @default.
- W72436669 hasConcept C2775960820 @default.
- W72436669 hasConcept C2776867660 @default.
- W72436669 hasConcept C2777831278 @default.
- W72436669 hasConcept C2778399450 @default.
- W72436669 hasConcept C2779306644 @default.
- W72436669 hasConcept C2780689927 @default.
- W72436669 hasConcept C71924100 @default.
- W72436669 hasConcept C90924648 @default.
- W72436669 hasConceptScore W72436669C110586980 @default.
- W72436669 hasConceptScore W72436669C126322002 @default.
- W72436669 hasConceptScore W72436669C134018914 @default.
- W72436669 hasConceptScore W72436669C139719470 @default.
- W72436669 hasConceptScore W72436669C142724271 @default.
- W72436669 hasConceptScore W72436669C162324750 @default.
- W72436669 hasConceptScore W72436669C170493617 @default.
- W72436669 hasConceptScore W72436669C204787440 @default.
- W72436669 hasConceptScore W72436669C2775960820 @default.
- W72436669 hasConceptScore W72436669C2776867660 @default.
- W72436669 hasConceptScore W72436669C2777831278 @default.
- W72436669 hasConceptScore W72436669C2778399450 @default.
- W72436669 hasConceptScore W72436669C2779306644 @default.
- W72436669 hasConceptScore W72436669C2780689927 @default.
- W72436669 hasConceptScore W72436669C71924100 @default.
- W72436669 hasConceptScore W72436669C90924648 @default.
- W72436669 hasIssue "7" @default.
- W72436669 hasLocation W724366691 @default.
- W72436669 hasOpenAccess W72436669 @default.
- W72436669 hasPrimaryLocation W724366691 @default.
- W72436669 hasRelatedWork W1607400749 @default.
- W72436669 hasRelatedWork W1975650642 @default.
- W72436669 hasRelatedWork W2010140898 @default.
- W72436669 hasRelatedWork W2012394330 @default.
- W72436669 hasRelatedWork W2087751406 @default.
- W72436669 hasRelatedWork W2089387278 @default.
- W72436669 hasRelatedWork W2089518257 @default.
- W72436669 hasRelatedWork W2107322230 @default.
- W72436669 hasRelatedWork W2156844778 @default.
- W72436669 hasRelatedWork W1950451770 @default.
- W72436669 hasVolume "24" @default.
- W72436669 isParatext "false" @default.
- W72436669 isRetracted "false" @default.
- W72436669 magId "72436669" @default.
- W72436669 workType "article" @default.