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• W72454080 abstract "Publisher Summary This chapter discusses humoral control of ventilation during exercise in man. To determine the importance of humoral control of the exercise hyperpnea, human subjects exercising on a cycle ergometer were studied, utilizing several dynamic work rate forcing regimes. The response to these exercise perturbations were established, with emphasis on the time course of ventilation, gas exchange, blood gas and acid–base variables. The imposed work rate forcings included the following: (1) incremental tests to the limit of subject tolerance either with a staircase or ramp pattern, (2) square waves to work rates both less than and greater than the subjects anaerobic threshold (AT), and (3) sine wave patterns with periods ranging from 0.5 to 10 min. Tests were performed by normal subjects breathing air or breathing various inspired O2 concentrations and also with induced metabolic acidosis or alkalosis. During exercise of moderate work intensity, arterial pH, PaCO2, and PO2 are regulated near resting levels in spite of considerable increases in CO2 production and O2 consumption. The observation that these chemical reflections of metabolism remain relatively unchanged suggests that alveolar ventilation increases during exercise in proportion to the increase in metabolic rate." @default.
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• W72454080 date "1981-01-01" @default.
• W72454080 modified "2023-09-26" @default.
• W72454080 title "HUMORAL CONTROL OF VENTILATION DURING EXERCISE IN MAN" @default.
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• W72454080 doi "https://doi.org/10.1016/b978-0-08-026823-1.50038-7" @default.
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