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- W72582747 abstract "Lung cancer is the leading cause of cancer deaths worldwide. It has overtaken breast cancer as the leading cause of cancer death in women, due largely to increased incidence of smoking among women, as well as adolescents of both sexes. Though the relationship between lung cancer and tobacco is well described, smoking cessation efforts have had limited success. Lung cancer incidence for 2002 was estimated to be 174,300; the projected number of deaths was 157,700 (1). Early detection methods have also been largely unsuccessful—no benefit of screening with chest radiographs or CT scans has been demonstrated, although studies are ongoing. Over the past 40 yr, the overall survival rate has improved only slightly as surgery, radiation therapy, and chemotherapy remain the mainstays of current treatment. Therapies with novel targeted agents are currently under active investigation in all settings of treatment. Primary lung cancer prevention efforts focus on educating people not to begin smoking; secondary prevention involves cessation efforts; and chemoprevention targets reversal of premalignant lesions and prevention of second primary tumors (SPTs) in patients with a prior history of cancer." @default.
- W72582747 created "2016-06-24" @default.
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- W72582747 date "2008-08-15" @default.
- W72582747 modified "2023-09-25" @default.
- W72582747 title "Strategies in Lung Cancer Chemoprevention" @default.
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- W72582747 doi "https://doi.org/10.1007/978-1-59259-768-0_22" @default.
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