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- W72746412 abstract "The pancreatic islet is a complex mini-organ that plays an essential role in regulating the metabolic environment of organisms by sensing nutrients such as glucose and then responding with regulated hormone secretion. This chapter focuses on recent advances in our understanding of the anatomic structure and architecture of the human pancreatic islet in health and in disease. Much of this progress results from the increased availability of human islets and human pancreatic tissue to a large number of scientists and efforts by scientists to translate information from cell lines and animal models into human tissues and samples. The human islet has many similarities to the islets from other species, but it does have some distinctive features such as cell composition and arrangement, vascularization, and islet innervation. Recent studies of human pancreas from individuals with type 1 or type 2 diabetes has provided insight into disease pathogenesis and raised new questions that challenge disease paradigms." @default.
- W72746412 created "2016-06-24" @default.
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- W72746412 date "2014-01-01" @default.
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- W72746412 title "Architecture and Morphology of Human Pancreatic Islets" @default.
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- W72746412 doi "https://doi.org/10.1016/b978-0-12-408134-5.00016-0" @default.
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