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- W72946955 abstract "Mice were fed with high zinc diet (15 g/kg) for 3 weeks. High zinc could cause liver toxicity: 1. inhibiting the activity of GOT and GPT in liver homogenate, reducing GSH and glycogen contents. 2. increasing the activity of aniline hydroxylase and inhibiting the activities of NADPH-cytochrome C reducease, benzo-phytamine-N-demethylase and glutathione S-transferase. The activities of cytochrome P450 and cytochrome b5 were not obviously changed 3. increasing microsomal membrane fluidity in the superficial layers, but not in the deep layers." @default.
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- W72946955 date "1998-05-01" @default.
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- W72946955 title "[Effects of high dietary zinc on liver function, hepatic drug metabolism enzymes and membrane fluidity in mice]." @default.
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