Matches in SemOpenAlex for { <https://semopenalex.org/work/W72979498> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W72979498 endingPage "5" @default.
- W72979498 startingPage "74" @default.
- W72979498 abstract "Pulmonary hypertension continues to be a major cause of morbidity and mortality, despite new treatments. Since inhaled nitric oxide has been reported to be effective in some cases, we investigated using nebulized nitroglycerine to treat pulmonary hypertension in children with congenital heart disease. Four children (ages 6-72 months) with severe pulmonary hypertension secondary to congenital heart disease (all with membranous ventricular septal defect, undergoing cardiac catheterization) were given 3 cc of nebulized normal saline over 10 min as placebo control, followed by nebulized nitroglycerine (20 micrograms/Kg in 3 cc normal saline). Normal saline administration did not elicit any change, but nitroglycerine administration resulted in the following changes (mean +/- SE, paired statistics): systolic pulmonary artery pressure from 68 +/- 8 to 53 +/- 6 at 10 min into treatment (P 0.006), mean pulmonary artery pressure 47 +/- 4 to 38 +/- 4 (P 0.005), heart rate 131 +/- 8 to 127 +/- 7 (P 0.13), systolic blood pressure 85 +/- 8 to 88 +/- 3 (P 0.7), mean blood pressure 59 +/- 6 to 63 +/- 4 (P 0.5). These results indicate that nebulized nitroglycerine may be an effective, easy to administer, inexpensive, and safe alternative for treatment of severe pulmonary hypertension in children with congenital heart disease, especially in areas where other treatments such as extracorporeal membrane oxygenation or inhaled nitric oxide are inaccessible." @default.
- W72979498 created "2016-06-24" @default.
- W72979498 creator A5057467500 @default.
- W72979498 creator A5059203169 @default.
- W72979498 creator A5087612178 @default.
- W72979498 creator A5088609876 @default.
- W72979498 date "1999-04-24" @default.
- W72979498 modified "2023-09-26" @default.
- W72979498 title "Nebulized nitroglycerin in children with pulmonary hypertension secondary to congenital heart disease." @default.
- W72979498 cites W1907994445 @default.
- W72979498 cites W2017402165 @default.
- W72979498 cites W2068600461 @default.
- W72979498 cites W2092145002 @default.
- W72979498 cites W2128139551 @default.
- W72979498 cites W2169182236 @default.
- W72979498 cites W2415662714 @default.
- W72979498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10214095" @default.
- W72979498 hasPublicationYear "1999" @default.
- W72979498 type Work @default.
- W72979498 sameAs 72979498 @default.
- W72979498 citedByCount "6" @default.
- W72979498 countsByYear W729794982014 @default.
- W72979498 countsByYear W729794982015 @default.
- W72979498 crossrefType "journal-article" @default.
- W72979498 hasAuthorship W72979498A5057467500 @default.
- W72979498 hasAuthorship W72979498A5059203169 @default.
- W72979498 hasAuthorship W72979498A5087612178 @default.
- W72979498 hasAuthorship W72979498A5088609876 @default.
- W72979498 hasConcept C126322002 @default.
- W72979498 hasConcept C164705383 @default.
- W72979498 hasConcept C2776858399 @default.
- W72979498 hasConcept C2777385415 @default.
- W72979498 hasConcept C2777397205 @default.
- W72979498 hasConcept C2780074459 @default.
- W72979498 hasConcept C2780930700 @default.
- W72979498 hasConcept C2780940725 @default.
- W72979498 hasConcept C42219234 @default.
- W72979498 hasConcept C71924100 @default.
- W72979498 hasConcept C84393581 @default.
- W72979498 hasConceptScore W72979498C126322002 @default.
- W72979498 hasConceptScore W72979498C164705383 @default.
- W72979498 hasConceptScore W72979498C2776858399 @default.
- W72979498 hasConceptScore W72979498C2777385415 @default.
- W72979498 hasConceptScore W72979498C2777397205 @default.
- W72979498 hasConceptScore W72979498C2780074459 @default.
- W72979498 hasConceptScore W72979498C2780930700 @default.
- W72979498 hasConceptScore W72979498C2780940725 @default.
- W72979498 hasConceptScore W72979498C42219234 @default.
- W72979498 hasConceptScore W72979498C71924100 @default.
- W72979498 hasConceptScore W72979498C84393581 @default.
- W72979498 hasIssue "2" @default.
- W72979498 hasLocation W729794981 @default.
- W72979498 hasOpenAccess W72979498 @default.
- W72979498 hasPrimaryLocation W729794981 @default.
- W72979498 hasRelatedWork W1968716161 @default.
- W72979498 hasRelatedWork W2104390255 @default.
- W72979498 hasRelatedWork W2112249460 @default.
- W72979498 hasRelatedWork W2345820343 @default.
- W72979498 hasRelatedWork W2362525150 @default.
- W72979498 hasRelatedWork W2379383919 @default.
- W72979498 hasRelatedWork W2389265429 @default.
- W72979498 hasRelatedWork W2406412656 @default.
- W72979498 hasRelatedWork W2918059625 @default.
- W72979498 hasRelatedWork W72979498 @default.
- W72979498 hasVolume "95" @default.
- W72979498 isParatext "false" @default.
- W72979498 isRetracted "false" @default.
- W72979498 magId "72979498" @default.
- W72979498 workType "article" @default.