Matches in SemOpenAlex for { <https://semopenalex.org/work/W73165026> ?p ?o ?g. }
- W73165026 abstract "Abstract Chromatin structure undergoes many changes during the cell cycle and in response to regulatory events. A basic unit of chromatin organization is the nucleosome core particle. However, very little is known about how nucleosomes are arranged into higher-order structures in vivo, even though the efficiency and precision of cell division imply high levels of structural organization. We propose abandoning the current paradigm of chromatin organization based on thermodynamics of the lowest energy state and replace it with the idea of a topologically restrained, high-energy structure. We propose that DNA is subject to a recursive topological restraint, and is anchored by hemicatenates that are part of the chromosomal scaffold. Long-distance cis -regulation of transcription is a natural consequence of recursive topological restraint. This new theory of chromatin structure has a multitude of consequences for key aspects of cellular biology." @default.
- W73165026 created "2016-06-24" @default.
- W73165026 creator A5016335715 @default.
- W73165026 creator A5044422688 @default.
- W73165026 date "2008-12-18" @default.
- W73165026 modified "2023-10-16" @default.
- W73165026 title "Kinetic control of eukaryotic chromatin structure by recursive topological restraints" @default.
- W73165026 cites W112848905 @default.
- W73165026 cites W1544733640 @default.
- W73165026 cites W1877359570 @default.
- W73165026 cites W1896024261 @default.
- W73165026 cites W1901729158 @default.
- W73165026 cites W1916692694 @default.
- W73165026 cites W1927250746 @default.
- W73165026 cites W1935348556 @default.
- W73165026 cites W1948219789 @default.
- W73165026 cites W1953309509 @default.
- W73165026 cites W1963721134 @default.
- W73165026 cites W1966746380 @default.
- W73165026 cites W1968220818 @default.
- W73165026 cites W1968806977 @default.
- W73165026 cites W1968894421 @default.
- W73165026 cites W1971118090 @default.
- W73165026 cites W1971785251 @default.
- W73165026 cites W1972066468 @default.
- W73165026 cites W1973536007 @default.
- W73165026 cites W1974704110 @default.
- W73165026 cites W1975892599 @default.
- W73165026 cites W1976610198 @default.
- W73165026 cites W1976832393 @default.
- W73165026 cites W1977160003 @default.
- W73165026 cites W1978546008 @default.
- W73165026 cites W1984178639 @default.
- W73165026 cites W1984508588 @default.
- W73165026 cites W1989776223 @default.
- W73165026 cites W1991329281 @default.
- W73165026 cites W1992729225 @default.
- W73165026 cites W1993320197 @default.
- W73165026 cites W1994596486 @default.
- W73165026 cites W1999719667 @default.
- W73165026 cites W1999861460 @default.
- W73165026 cites W2001929989 @default.
- W73165026 cites W2002781605 @default.
- W73165026 cites W2003209186 @default.
- W73165026 cites W2003569868 @default.
- W73165026 cites W2004135086 @default.
- W73165026 cites W2004224703 @default.
- W73165026 cites W2004694336 @default.
- W73165026 cites W2004791849 @default.
- W73165026 cites W2007025396 @default.
- W73165026 cites W2007261798 @default.
- W73165026 cites W2007561670 @default.
- W73165026 cites W2007848866 @default.
- W73165026 cites W2012036437 @default.
- W73165026 cites W2017314177 @default.
- W73165026 cites W2018626566 @default.
- W73165026 cites W2018968363 @default.
- W73165026 cites W2022616695 @default.
- W73165026 cites W2024316977 @default.
- W73165026 cites W2030160368 @default.
- W73165026 cites W2032035535 @default.
- W73165026 cites W2034574779 @default.
- W73165026 cites W2035374814 @default.
- W73165026 cites W2035983538 @default.
- W73165026 cites W2036513942 @default.
- W73165026 cites W2037012605 @default.
- W73165026 cites W2037127704 @default.
- W73165026 cites W2038132544 @default.
- W73165026 cites W2038447185 @default.
- W73165026 cites W2038871793 @default.
- W73165026 cites W2040433610 @default.
- W73165026 cites W2041517407 @default.
- W73165026 cites W2045807153 @default.
- W73165026 cites W2046485956 @default.
- W73165026 cites W2049426834 @default.
- W73165026 cites W2050254783 @default.
- W73165026 cites W2054609805 @default.
- W73165026 cites W2059991470 @default.
- W73165026 cites W2061015334 @default.
- W73165026 cites W2063433107 @default.
- W73165026 cites W2064318074 @default.
- W73165026 cites W2069780448 @default.
- W73165026 cites W2070131671 @default.
- W73165026 cites W2070424720 @default.
- W73165026 cites W2071481152 @default.
- W73165026 cites W2074111939 @default.
- W73165026 cites W2074300717 @default.
- W73165026 cites W2074571991 @default.
- W73165026 cites W2079084847 @default.
- W73165026 cites W2079233107 @default.
- W73165026 cites W2084135444 @default.
- W73165026 cites W2085442496 @default.
- W73165026 cites W2087554148 @default.
- W73165026 cites W2091034793 @default.
- W73165026 cites W2092638438 @default.
- W73165026 cites W2094212271 @default.
- W73165026 cites W2096065245 @default.
- W73165026 cites W2097148598 @default.
- W73165026 cites W2100581810 @default.
- W73165026 cites W2104190830 @default.