Matches in SemOpenAlex for { <https://semopenalex.org/work/W7320268> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W7320268 endingPage "2256" @default.
- W7320268 startingPage "2252" @default.
- W7320268 abstract "Abstract Neutrophil chemotactic and functional defects occur in beta-thalassemia and in patients after bone marrow transplantation (BMT). Interleukin-8 (IL-8) is a novel chemotactic and activating peptide for neutrophils and can be detected in the circulation. IL-8 serum concentrations were evaluated in 30 beta-thalassemic patients before and after BMT. Serial samples from 16 patients were also studied. Fourteen sera from healthy children, 43 patients with chronic viral hepatitis, 16 patients on chronic transfusion treatment for various hematologic disorders, and 28 healthy adults were studied as controls. IL-8 was evaluated by an enzyme-linked immunosorbent assay. Patients with beta-thalassemia had higher IL-8 concentrations than did normal controls, patients with liver disease, and patients on chronic transfusion. beta-Thalassemic patients with severe liver siderosis and fibrosis had the highest IL-8 concentrations. After BMT in patients with successful engraftment, IL-8 concentrations decreased significantly. In contrast, in patients with acute graft-versus-host disease (GVHD), IL-8 concentrations were not statistically different from the concentrations found before BMT and were higher than in patients with no complications and patients with graft rejection. IL-8 may play a part in the immune dysregulation that occurs in beta-thalassemia and may be involved in the immune mechanisms leading to GVHD." @default.
- W7320268 created "2016-06-24" @default.
- W7320268 creator A5009186565 @default.
- W7320268 creator A5015756254 @default.
- W7320268 creator A5017107411 @default.
- W7320268 creator A5032296033 @default.
- W7320268 creator A5033086164 @default.
- W7320268 creator A5079844728 @default.
- W7320268 creator A5090198551 @default.
- W7320268 date "1993-05-01" @default.
- W7320268 modified "2023-09-30" @default.
- W7320268 title "Elevated interleukin-8 serum concentrations in beta-thalassemia and graft-versus-host disease" @default.
- W7320268 cites W1516892952 @default.
- W7320268 cites W1829192223 @default.
- W7320268 cites W194379350 @default.
- W7320268 cites W2050714466 @default.
- W7320268 cites W2071258337 @default.
- W7320268 cites W2072036820 @default.
- W7320268 cites W2086475919 @default.
- W7320268 cites W2089128024 @default.
- W7320268 cites W2143951873 @default.
- W7320268 cites W2159833023 @default.
- W7320268 cites W2315168906 @default.
- W7320268 cites W2399493597 @default.
- W7320268 cites W2399665308 @default.
- W7320268 doi "https://doi.org/10.1182/blood.v81.9.2252.2252" @default.
- W7320268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8481507" @default.
- W7320268 hasPublicationYear "1993" @default.
- W7320268 type Work @default.
- W7320268 sameAs 7320268 @default.
- W7320268 citedByCount "45" @default.
- W7320268 countsByYear W73202682012 @default.
- W7320268 countsByYear W73202682013 @default.
- W7320268 countsByYear W73202682014 @default.
- W7320268 countsByYear W73202682016 @default.
- W7320268 countsByYear W73202682017 @default.
- W7320268 countsByYear W73202682019 @default.
- W7320268 countsByYear W73202682023 @default.
- W7320268 crossrefType "journal-article" @default.
- W7320268 hasAuthorship W7320268A5009186565 @default.
- W7320268 hasAuthorship W7320268A5015756254 @default.
- W7320268 hasAuthorship W7320268A5017107411 @default.
- W7320268 hasAuthorship W7320268A5032296033 @default.
- W7320268 hasAuthorship W7320268A5033086164 @default.
- W7320268 hasAuthorship W7320268A5079844728 @default.
- W7320268 hasAuthorship W7320268A5090198551 @default.
- W7320268 hasBestOaLocation W73202681 @default.
- W7320268 hasConcept C126322002 @default.
- W7320268 hasConcept C203014093 @default.
- W7320268 hasConcept C2777799968 @default.
- W7320268 hasConcept C2777940137 @default.
- W7320268 hasConcept C2779972918 @default.
- W7320268 hasConcept C2780883591 @default.
- W7320268 hasConcept C2911091166 @default.
- W7320268 hasConcept C71924100 @default.
- W7320268 hasConcept C8891405 @default.
- W7320268 hasConcept C90924648 @default.
- W7320268 hasConceptScore W7320268C126322002 @default.
- W7320268 hasConceptScore W7320268C203014093 @default.
- W7320268 hasConceptScore W7320268C2777799968 @default.
- W7320268 hasConceptScore W7320268C2777940137 @default.
- W7320268 hasConceptScore W7320268C2779972918 @default.
- W7320268 hasConceptScore W7320268C2780883591 @default.
- W7320268 hasConceptScore W7320268C2911091166 @default.
- W7320268 hasConceptScore W7320268C71924100 @default.
- W7320268 hasConceptScore W7320268C8891405 @default.
- W7320268 hasConceptScore W7320268C90924648 @default.
- W7320268 hasIssue "9" @default.
- W7320268 hasLocation W73202681 @default.
- W7320268 hasOpenAccess W7320268 @default.
- W7320268 hasPrimaryLocation W73202681 @default.
- W7320268 hasRelatedWork W2000471540 @default.
- W7320268 hasRelatedWork W2139190582 @default.
- W7320268 hasRelatedWork W2156949915 @default.
- W7320268 hasRelatedWork W2514522572 @default.
- W7320268 hasRelatedWork W2981521449 @default.
- W7320268 hasRelatedWork W3154160595 @default.
- W7320268 hasRelatedWork W3211078971 @default.
- W7320268 hasRelatedWork W4232041701 @default.
- W7320268 hasRelatedWork W4281783196 @default.
- W7320268 hasRelatedWork W7320268 @default.
- W7320268 hasVolume "81" @default.
- W7320268 isParatext "false" @default.
- W7320268 isRetracted "false" @default.
- W7320268 magId "7320268" @default.
- W7320268 workType "article" @default.