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- W73255819 abstract "Background: Cardiovascular disease (CVD) is the Leading cause of mortality worldwide. Traditional risk factors of CVD have modest predictive power and discrimination. New biomarkers for CVD prediction are urgently required. Hypothesis: We used 1H NMR metabonomic profiling of serum to identify novel biomarkers of CVD. METHODS: We investigated 9,179 men and women, recruited between 2002-2008, participating in the London Life Sciences Population (LOLIPOP) study. Participants were followed up for CVD mortality to July 2011 (mean 5.5 years per person) and were assessed for CVD risk factors, including smoking, body mass index, blood pressure, fasting glucose and lipid profile. 1H NMR metabonomic profiling was done on baseline serum sample by 12T Bruker spectrometer, with quantification of 44 fatty acid and low molecular weight markers. RESULTS: There were 161 CVD deaths. Traditional risk factors were higher in people with CVD death compared to survivors (Table, all P<0.001). Framingham risk scores were higher i..." @default.
- W73255819 created "2016-06-24" @default.
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- W73255819 date "2013-11-26" @default.
- W73255819 modified "2023-09-28" @default.
- W73255819 title "Abstract 15746: Novel Metabolic Biomarkers Predict Cardiovascular Mortality" @default.
- W73255819 hasPublicationYear "2013" @default.
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