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- W73397246 abstract "TWO MAIN GERMS: The risk of severe complications of acute bacterial sinusitis warrants empirical antibiotic therapy targeted against the two main causal agents: S. pneumoniae and H. influenzae.A double-blind placebo-controlled randomized multicentric study conducted with two treatment arms including 310 patients has demonstrated that pristinamycin, 2 g/d for 8 days, has a clinical efficacy equivalent to cefuroxime axetil, 500 mg/d.Pristinamycin is an interesting alternative to beta-lactams for the first intention treatment of purulent acute sinusitis in adults. Its efficacy against penicillin-resistant pneumococci and H. influenzae is a further reason for its use in case of failure after conventional treatments." @default.
- W73397246 created "2016-06-24" @default.
- W73397246 creator A5076537230 @default.
- W73397246 date "1999-09-04" @default.
- W73397246 modified "2023-09-23" @default.
- W73397246 title "[Pristinamycin in the outpatient treatment of acute sinusitis in adults]." @default.
- W73397246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10506877" @default.
- W73397246 hasPublicationYear "1999" @default.
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