Matches in SemOpenAlex for { <https://semopenalex.org/work/W73603108> ?p ?o ?g. }
- W73603108 endingPage "67" @default.
- W73603108 startingPage "43" @default.
- W73603108 abstract "Publisher Summary This chapter discusses the isolation and characterization of immunoglobulins, antibodies, and their constituent polypeptide chains. Immunoglobulins consist of a highly heterogeneous group of macromolecules with respect to charge, mass, and biological activity. They represent the most basic globulins of the serum and exhibit the least electrophoretic mobility. Their separation from the other serum proteins requires the use of conventional physicochemical means such as salt precipitation, ion-exchange chromatography, gel filtration, preparative zonal electrophoresis, or affinity chromatography, the latter method being particularly well suited to the isolation of specific antibodies from sera. Immunoglobulins of various species possess different electrical charges and masses and consequently may exhibit different electrophoretic behaviors, which implies that a fractionation procedure particularly successful for the isolation of immunoglobulin from one animal species may not necessarily be directly applicable to the isolation of immunoglobulins of another species. Affinity chromatography has the advantage of being rapid and specific and provides isolated antibodies in good yield. It affords a means to selectively isolate, from the same serum, several antibody components exhibiting different affinities for an antigen. This method is particularly well suited for the separation of antibodies against protein antigens such as hemocyanin, bovine serum albumin, hapten–protein conjugates, and glycoproteins and of antibodies against polysaccharide antigens." @default.
- W73603108 created "2016-06-24" @default.
- W73603108 creator A5007585196 @default.
- W73603108 creator A5016552175 @default.
- W73603108 creator A5039837300 @default.
- W73603108 date "1979-01-01" @default.
- W73603108 modified "2023-10-18" @default.
- W73603108 title "The Isolation and Characterization of Immunoglobulins, Antibodies, and Their Constituent Polypeptide Chains" @default.
- W73603108 cites W121396384 @default.
- W73603108 cites W1476591324 @default.
- W73603108 cites W1517425383 @default.
- W73603108 cites W1553961202 @default.
- W73603108 cites W1565089576 @default.
- W73603108 cites W1579116430 @default.
- W73603108 cites W1586757195 @default.
- W73603108 cites W1588885776 @default.
- W73603108 cites W159228040 @default.
- W73603108 cites W1625660792 @default.
- W73603108 cites W1899011329 @default.
- W73603108 cites W1965933027 @default.
- W73603108 cites W1973812271 @default.
- W73603108 cites W1983148679 @default.
- W73603108 cites W1990344075 @default.
- W73603108 cites W1997133987 @default.
- W73603108 cites W1999047723 @default.
- W73603108 cites W2001184763 @default.
- W73603108 cites W2015238774 @default.
- W73603108 cites W2024114852 @default.
- W73603108 cites W2038443775 @default.
- W73603108 cites W2040274742 @default.
- W73603108 cites W2047374628 @default.
- W73603108 cites W2054166182 @default.
- W73603108 cites W2060859538 @default.
- W73603108 cites W2068850000 @default.
- W73603108 cites W2069201433 @default.
- W73603108 cites W2070149310 @default.
- W73603108 cites W2071619300 @default.
- W73603108 cites W2072170578 @default.
- W73603108 cites W2074546182 @default.
- W73603108 cites W2075032348 @default.
- W73603108 cites W2080779467 @default.
- W73603108 cites W2090883793 @default.
- W73603108 cites W2093237073 @default.
- W73603108 cites W2094185721 @default.
- W73603108 cites W2100837269 @default.
- W73603108 cites W2130766080 @default.
- W73603108 cites W2244559125 @default.
- W73603108 cites W2317334995 @default.
- W73603108 cites W2321537879 @default.
- W73603108 cites W2335092521 @default.
- W73603108 cites W2344139199 @default.
- W73603108 cites W2405070471 @default.
- W73603108 cites W2425358686 @default.
- W73603108 cites W4236144669 @default.
- W73603108 cites W4240837164 @default.
- W73603108 cites W4249458489 @default.
- W73603108 cites W4313377124 @default.
- W73603108 cites W4321713760 @default.
- W73603108 cites W80772389 @default.
- W73603108 doi "https://doi.org/10.1016/b978-0-12-442750-1.50007-3" @default.
- W73603108 hasPublicationYear "1979" @default.
- W73603108 type Work @default.
- W73603108 sameAs 73603108 @default.
- W73603108 citedByCount "9" @default.
- W73603108 crossrefType "book-chapter" @default.
- W73603108 hasAuthorship W73603108A5007585196 @default.
- W73603108 hasAuthorship W73603108A5016552175 @default.
- W73603108 hasAuthorship W73603108A5039837300 @default.
- W73603108 hasConcept C159654299 @default.
- W73603108 hasConcept C171250308 @default.
- W73603108 hasConcept C185592680 @default.
- W73603108 hasConcept C192562407 @default.
- W73603108 hasConcept C203014093 @default.
- W73603108 hasConcept C2775941552 @default.
- W73603108 hasConcept C2780841128 @default.
- W73603108 hasConcept C70721500 @default.
- W73603108 hasConcept C86803240 @default.
- W73603108 hasConcept C89423630 @default.
- W73603108 hasConceptScore W73603108C159654299 @default.
- W73603108 hasConceptScore W73603108C171250308 @default.
- W73603108 hasConceptScore W73603108C185592680 @default.
- W73603108 hasConceptScore W73603108C192562407 @default.
- W73603108 hasConceptScore W73603108C203014093 @default.
- W73603108 hasConceptScore W73603108C2775941552 @default.
- W73603108 hasConceptScore W73603108C2780841128 @default.
- W73603108 hasConceptScore W73603108C70721500 @default.
- W73603108 hasConceptScore W73603108C86803240 @default.
- W73603108 hasConceptScore W73603108C89423630 @default.
- W73603108 hasLocation W736031081 @default.
- W73603108 hasOpenAccess W73603108 @default.
- W73603108 hasPrimaryLocation W736031081 @default.
- W73603108 hasRelatedWork W2316445883 @default.
- W73603108 hasRelatedWork W2800902349 @default.
- W73603108 hasRelatedWork W2949362246 @default.
- W73603108 hasRelatedWork W2949911667 @default.
- W73603108 hasRelatedWork W2951449457 @default.
- W73603108 hasRelatedWork W2952100114 @default.
- W73603108 hasRelatedWork W2952309663 @default.