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- W73672671 abstract "The antiviral efficacy of interferon-α (IFN-α) therapy for chronic hepatitis B (CHB) is not only related to DNA load and genetype of H B V b e f o r e t r e a t m e n t , g e n e m u t a t i o n o f HBV and polymorphism of type II HLA in the host, but also depends on the immunity of CHB patients. Researchers pay more and more attention to the mutant strain of virus and phenotypes of genes. However, the mechanism of interferon to resist HBV and the escape mechanism of HBV against the IFN therapy have not been clarified yet. This paper reviews the mechanism of IFN therapy and the influencing factors at molecular and genetic levels." @default.
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- W73672671 date "2009-01-01" @default.
- W73672671 modified "2023-09-27" @default.
- W73672671 title "Advance in molecular mechanism of interferon to treat chronic hepatitis B" @default.
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- W73672671 doi "https://doi.org/10.11569/wcjd.v17.i18.1803" @default.
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