Matches in SemOpenAlex for { <https://semopenalex.org/work/W73948939> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W73948939 endingPage "360" @default.
- W73948939 startingPage "355" @default.
- W73948939 abstract "The most common etiologic cause of thyrotoxicosis in children and adults is autoimmune Graves' (Basedow's) disease. Antithyroid medications, surgery and radioactive iodine have been used in the treatment of Graves' hyperthyroidism for more than six decades. The use of antithyroid drugs is the most common therapeutic approach. However, long-term remission with antithyroid drugs can be expected in 20-50% of adults and 20-30% of children. The methods for definitive treatment of Graves' hyperthyroidism are iodine-131 (radioiodine) and surgery. Both treatment modalities have benefits and risks and the decision is made according to the age, patient preference and the presence of other co-morbidities, individual characteristics of patients and the availability of certain treatment modality. Radioiodine is simple, safe, effective and economic procedure for definitive treatment of Graves' hyperthyroidism. It is administered ambulatory and can be given to the patient in thyrotoxicosis. Due to many benefits, radioiodine is preferred in most of the adult patients with Graves' hyperthyroidism while only small proportion of patients is sent to surgery. Radioiodine is especially the treatment of choice in elderly patients and patients with heart disease. In these patients radioiodine is indicated immediately after reaching euthyroidism with antithyroid drugs. Surgery is mainly indicated in younger patients, in the case of patient preference or in special indications. Clear indications for surgical treatment of Graves' hyperthyroidism are: suspected or confirmed malignancy, coexisting pathology that demands surgical treatment, pregnancy and breastfeeding, large goiter (> 80 grams) or goiter with symptoms and signs of compression, severe toxic side effects of antithyroid medications, requirement for immediate control of disease, age younger than 5 years and active ophtalmopathy. The risk of surgical treatment is negatively correlated with the surgeon's experience and nowadays, total or near-total thyroidectomy is preferred surgical approach. End point of both treatment modalities is usually hypothyroidism that should not be considered as the consequence of treatment. Moreover, due to thyroid hormones replacement therapy equilibrium can be easily achieved." @default.
- W73948939 created "2016-06-24" @default.
- W73948939 creator A5000511004 @default.
- W73948939 creator A5001799711 @default.
- W73948939 creator A5006455341 @default.
- W73948939 creator A5033398142 @default.
- W73948939 date "2010-11-01" @default.
- W73948939 modified "2023-10-03" @default.
- W73948939 title "[Radioiodine versus surgery in the treatment of Graves' hyperthyroidism]." @default.
- W73948939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21294325" @default.
- W73948939 hasPublicationYear "2010" @default.
- W73948939 type Work @default.
- W73948939 sameAs 73948939 @default.
- W73948939 citedByCount "2" @default.
- W73948939 countsByYear W739489392018 @default.
- W73948939 crossrefType "journal-article" @default.
- W73948939 hasAuthorship W73948939A5000511004 @default.
- W73948939 hasAuthorship W73948939A5001799711 @default.
- W73948939 hasAuthorship W73948939A5006455341 @default.
- W73948939 hasAuthorship W73948939A5033398142 @default.
- W73948939 hasConcept C126322002 @default.
- W73948939 hasConcept C141071460 @default.
- W73948939 hasConcept C187212893 @default.
- W73948939 hasConcept C2776254400 @default.
- W73948939 hasConcept C2776606491 @default.
- W73948939 hasConcept C2776652619 @default.
- W73948939 hasConcept C2779134260 @default.
- W73948939 hasConcept C2908975369 @default.
- W73948939 hasConcept C2909564963 @default.
- W73948939 hasConcept C35785553 @default.
- W73948939 hasConcept C526584372 @default.
- W73948939 hasConcept C71924100 @default.
- W73948939 hasConceptScore W73948939C126322002 @default.
- W73948939 hasConceptScore W73948939C141071460 @default.
- W73948939 hasConceptScore W73948939C187212893 @default.
- W73948939 hasConceptScore W73948939C2776254400 @default.
- W73948939 hasConceptScore W73948939C2776606491 @default.
- W73948939 hasConceptScore W73948939C2776652619 @default.
- W73948939 hasConceptScore W73948939C2779134260 @default.
- W73948939 hasConceptScore W73948939C2908975369 @default.
- W73948939 hasConceptScore W73948939C2909564963 @default.
- W73948939 hasConceptScore W73948939C35785553 @default.
- W73948939 hasConceptScore W73948939C526584372 @default.
- W73948939 hasConceptScore W73948939C71924100 @default.
- W73948939 hasLocation W739489391 @default.
- W73948939 hasLocation W739489392 @default.
- W73948939 hasOpenAccess W73948939 @default.
- W73948939 hasPrimaryLocation W739489391 @default.
- W73948939 hasRelatedWork W1582198706 @default.
- W73948939 hasRelatedWork W1759091480 @default.
- W73948939 hasRelatedWork W179995436 @default.
- W73948939 hasRelatedWork W1800809727 @default.
- W73948939 hasRelatedWork W1894430052 @default.
- W73948939 hasRelatedWork W193831611 @default.
- W73948939 hasRelatedWork W1970761739 @default.
- W73948939 hasRelatedWork W1991183780 @default.
- W73948939 hasRelatedWork W2061694851 @default.
- W73948939 hasRelatedWork W2205037416 @default.
- W73948939 hasRelatedWork W2274925924 @default.
- W73948939 hasRelatedWork W2328100076 @default.
- W73948939 hasRelatedWork W2333670179 @default.
- W73948939 hasRelatedWork W2395300957 @default.
- W73948939 hasRelatedWork W2442822981 @default.
- W73948939 hasRelatedWork W2473280767 @default.
- W73948939 hasRelatedWork W2795184109 @default.
- W73948939 hasRelatedWork W2972065880 @default.
- W73948939 hasRelatedWork W57386123 @default.
- W73948939 hasRelatedWork W2170939878 @default.
- W73948939 hasVolume "132" @default.
- W73948939 isParatext "false" @default.
- W73948939 isRetracted "false" @default.
- W73948939 magId "73948939" @default.
- W73948939 workType "article" @default.