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- W745919197 endingPage "1044" @default.
- W745919197 startingPage "1030" @default.
- W745919197 abstract "This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It does not establish an exhaustive list of the works in this field but rather propose constructive criticisms pointing out critical factors that could improve the nano-radiation therapy. Whereas most reviews show the chemists and/or biologists points of view, the present analysis is also seen through the prism of the medical physicist. In particular, we described and evaluated the influence of X-rays energy spectra using a numerical analysis. We observed a lack of standardization in preclinical studies that could partially explain the low number of translation to clinical applications for this innovative therapeutic strategy. Pointing out the critical parameters of high-Z nanoparticles radiosensitization, this review is expected to contribute to a larger preclinical and clinical development." @default.
- W745919197 created "2016-06-24" @default.
- W745919197 creator A5003899960 @default.
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- W745919197 creator A5063251608 @default.
- W745919197 creator A5068586945 @default.
- W745919197 date "2015-01-01" @default.
- W745919197 modified "2023-10-09" @default.
- W745919197 title "Nanoparticles for Radiation Therapy Enhancement: the Key Parameters" @default.
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- W745919197 doi "https://doi.org/10.7150/thno.11642" @default.
- W745919197 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4493540" @default.
- W745919197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26155318" @default.