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- W747014512 abstract "We conducted a case-control study to investigate the association between the survivin rs9904341 G<C polymorphism and risk of pancreatic cancer. A total of 261 pancreatic cancer patients who were pathologically confirmed to have pancreatic cancer were included in the study. Polymorphisms of rs9904341 G<C were assessed by polymerase chain reaction-restriction fragment length polymorphism. Pancreatic cancer patients were more likely to be smokers, have a family history of cancer, and have diabetes. Using multivariate logistic regression analysis, the CC genotype was found to be associated with a significantly increased risk of pancreatic cancer risk compared with the GG genotype (odds ratio = 1.85, 95% confidence interval = 1.12-3.01). Moreover, those carrying the C allele had a higher risk of pancreatic cancer compared to those with the G allele (odds ratio = 1.38, 95% confidence interval = 1.08-1.77). In conclusion, we found that the survivin rs9904341 polymorphism was associated with an increased risk of acute pancreatitis." @default.
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- W747014512 date "2015-01-01" @default.
- W747014512 modified "2023-09-29" @default.
- W747014512 title "Association between rs9904341 G<C gene polymorphism and susceptibility to pancreatic cancer in a Chinese population" @default.
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- W747014512 doi "https://doi.org/10.4238/2015.may.18.10" @default.
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