Matches in SemOpenAlex for { <https://semopenalex.org/work/W74817580> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W74817580 abstract "Since the early reports of methicillin resistance in Staphylococcus aureus in the mid twentieth century, antibiotic resistance has been an important health issue. Multidrug resistance (MDR) has subsequently been identified as a problem in healthcare due to its association with increased treatment options and costs. Despite the problems of resistance, antibiotics remain an important therapeutic option for bacterial infections in humans. Antimicrobial properties have also been identified in various plants products including essential oils (EOs). In this study, a S. aureus isolate was screened for susceptibility to different antibiotic groups and EOs.Methods:Antibiotic susceptibility testing based on the BSAC guidelines was performed on the isolate. the antibiotics tested included cefoxitin, tetracycline, gentamicin, ciprofloxacin, erythromycin and rifampicin. Multiplex PCR was also performed to determine the presence/absence of the PVL gene and mecA in this isolate. The effect of EOs (lemongrass, grapefruit, lime, bergamot, citral, geranium, lemon and limonene) against the S. aureus strain was tested using disc diffusion assay and determination of MICs and MBCs.Results:The S. aureus isolate was resistant to four of six antibiotic groups including methicillin. However the isolate was inhibited by different EOs lemongrass, grapefruit, lime, bergamot, citral, geranium however lemon EO and limonene did not inhibit the S. aureus isolate. The most inhibitive activity (100%) was observed with Lemongrass EO and citral. The MIC of the EOs ranged between 0.03% and 2% (v/v), while the MBCs ranged between 0.06% and >4% (v/v).Conclusions:The EOs tested in this study demonstrated antimicrobial activity against a multi antibiotic resistant isolate and can be potentially used as a therapeutic option to reduce bacterial colonisation ex vivo." @default.
- W74817580 created "2016-06-24" @default.
- W74817580 creator A5006388165 @default.
- W74817580 creator A5057196485 @default.
- W74817580 creator A5082339410 @default.
- W74817580 date "2013-11-01" @default.
- W74817580 modified "2023-09-27" @default.
- W74817580 title "The susceptibility of a PVL-negative Staphylococcus aureus isolate to antibiotics and essential oils" @default.
- W74817580 hasPublicationYear "2013" @default.
- W74817580 type Work @default.
- W74817580 sameAs 74817580 @default.
- W74817580 citedByCount "0" @default.
- W74817580 crossrefType "journal-article" @default.
- W74817580 hasAuthorship W74817580A5006388165 @default.
- W74817580 hasAuthorship W74817580A5057196485 @default.
- W74817580 hasAuthorship W74817580A5082339410 @default.
- W74817580 hasConcept C174802600 @default.
- W74817580 hasConcept C2776124114 @default.
- W74817580 hasConcept C2777278459 @default.
- W74817580 hasConcept C2778512257 @default.
- W74817580 hasConcept C2779489039 @default.
- W74817580 hasConcept C2781370763 @default.
- W74817580 hasConcept C31903555 @default.
- W74817580 hasConcept C4937899 @default.
- W74817580 hasConcept C501593827 @default.
- W74817580 hasConcept C523546767 @default.
- W74817580 hasConcept C54355233 @default.
- W74817580 hasConcept C86803240 @default.
- W74817580 hasConcept C89423630 @default.
- W74817580 hasConcept C94665300 @default.
- W74817580 hasConceptScore W74817580C174802600 @default.
- W74817580 hasConceptScore W74817580C2776124114 @default.
- W74817580 hasConceptScore W74817580C2777278459 @default.
- W74817580 hasConceptScore W74817580C2778512257 @default.
- W74817580 hasConceptScore W74817580C2779489039 @default.
- W74817580 hasConceptScore W74817580C2781370763 @default.
- W74817580 hasConceptScore W74817580C31903555 @default.
- W74817580 hasConceptScore W74817580C4937899 @default.
- W74817580 hasConceptScore W74817580C501593827 @default.
- W74817580 hasConceptScore W74817580C523546767 @default.
- W74817580 hasConceptScore W74817580C54355233 @default.
- W74817580 hasConceptScore W74817580C86803240 @default.
- W74817580 hasConceptScore W74817580C89423630 @default.
- W74817580 hasConceptScore W74817580C94665300 @default.
- W74817580 hasLocation W748175801 @default.
- W74817580 hasOpenAccess W74817580 @default.
- W74817580 hasPrimaryLocation W748175801 @default.
- W74817580 hasRelatedWork W2107417732 @default.
- W74817580 hasRelatedWork W2152296132 @default.
- W74817580 hasRelatedWork W2252438864 @default.
- W74817580 hasRelatedWork W2288332657 @default.
- W74817580 hasRelatedWork W2308199165 @default.
- W74817580 hasRelatedWork W2349881242 @default.
- W74817580 hasRelatedWork W2353974903 @default.
- W74817580 hasRelatedWork W2369651859 @default.
- W74817580 hasRelatedWork W2370411146 @default.
- W74817580 hasRelatedWork W2371731569 @default.
- W74817580 hasRelatedWork W2376637905 @default.
- W74817580 hasRelatedWork W2382313335 @default.
- W74817580 hasRelatedWork W2384572198 @default.
- W74817580 hasRelatedWork W2390249266 @default.
- W74817580 hasRelatedWork W2390809772 @default.
- W74817580 hasRelatedWork W2504439392 @default.
- W74817580 hasRelatedWork W3048918246 @default.
- W74817580 hasRelatedWork W3210403813 @default.
- W74817580 hasRelatedWork W2132244050 @default.
- W74817580 hasRelatedWork W2396067631 @default.
- W74817580 isParatext "false" @default.
- W74817580 isRetracted "false" @default.
- W74817580 magId "74817580" @default.
- W74817580 workType "article" @default.