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• W75070983 abstract "Taurine, which is synthesized from methionine in vivo, is a sulfur amino acid widely distributed in mammalian tissues, especially in brain, heart, and skeletal muscle. Taurine has been extensively studied for its cardiovascular actions. In stroke-prone spontaneously hypertensive rats (SHRSP) (Nara et al., 1978), spontaneously hypertensive rats (SHR) (Abe et al., 1987), and deoxycorticosterone acetate (DOCA)-salt hypertensive rats (Fujita and Sato, 1986; Inoue et al., 1988), the administration of taurine could attenuate the development of hypertension (Fig. 5.1). The antihypertensive effect of taurine is most pronounced in a salt-induced hypertensive model associated with increased sympathetic activity (Bouvier and de Champlain, 1986; Sato et al., 1991), such as the DOCA-salt rat (Fujita and Sato, 1986; Inoue et al., 1988). In addition, taurine has other cardiovascular actions, such as negative inotropic and positive chronotropic effects on heart (Huxtable and Sebring, 1982)." @default.
• W75070983 created "2016-06-24" @default.
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• W75070983 date "1992-01-01" @default.
• W75070983 modified "2023-09-28" @default.
• W75070983 title "Centrally Mediated Cardiovascular Effects of Taurine" @default.
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• W75070983 doi "https://doi.org/10.1007/978-1-4684-9184-5_5" @default.
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