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- W752902854 endingPage "198" @default.
- W752902854 startingPage "177" @default.
- W752902854 abstract "Animal grazing is a pervasive ecological factor threatening fungal fitness. This review summarizes the different approaches that have been used to test whether secondary metabolites serve as anti-fungivore defense agents. Assuming that secondary metabolites at least in part have evolved to mediate resistance against fungivores, this review evaluates the pros and cons of (1) using long-standing toxicity assays, (2) considering natural variation in fungal secondary metabolite formation, and (3) experiments with transgenic mutant fungi. Connecting inducible changes in fungal, molecular, genetic, biochemical, and morphological properties with fungivore behavioral and fitness assays is a new approach to investigate the functional relationship between secondary metabolite regulation and resistance against fungivores. Strengthening this dynamic view on fungus–fungivore interactions will certainly pave the way for a deeper understanding of how known (and still unknown) regulatory mechanisms act in concert with the biosynthesis of anti-fungivore compounds and the extent to which both constitutive and inducible variations in fungal chemical diversity represent an adaptation to animal grazing." @default.
- W752902854 created "2016-06-24" @default.
- W752902854 creator A5072517211 @default.
- W752902854 date "2015-01-01" @default.
- W752902854 modified "2023-09-24" @default.
- W752902854 title "Fungal Secondary Metabolism in the Light of Animal–Fungus Interactions: From Mechanism to Ecological Function" @default.
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