FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W753599254> ?p ?o ?g. }

• W753599254 endingPage "1053" @default.
• W753599254 startingPage "1030" @default.
• W753599254 abstract "1. The gastric mill central pattern generator (CPG) controls the chewing movements of teeth in the gastric mill of the lobster. This CPG has been extensively studied, but the precise mechanism underlying pattern generation is not well understood. The goal of this research was to develop a simplified model that captures the principle, biologically significant features of this CPG. We introduce a simplified neuron model that embodies approximations of well-known membrane currents, and is able to reproduce several global characteristics of gastric mill neurons. A network built with these neurons, using graded synaptic transmission and having the synaptic connections of the biological circuit, is sufficient to explain much of the network's behavior. 2. The cell model is a generalization and extension of the Van der Pol relaxation oscillator equations. It is described by two differential equations, one for current conservation and one for slow current activation. The model has a fast current that may, by adjusting one parameter, have a region of negative resistance in its current-voltage (I-V) curve. It also has a slow current with a single gain parameter that can be regarded as the combination of slow inward and outward currents. 3. For suitable values of the fast current parameter and the slow current parameter, the isolated model neuron exhibits several different behaviors: plateau potentials, postinhibitory rebound, postburst hyperpolarization, and endogenous oscillations. When the slow current is separated into inward and outward fractions with separately adjustable gain parameters, the model neuron can fire tonically, be quiescent, or generate spontaneous voltage oscillations with varying amounts of depolarization or hyperpolarization. 4. The most common form of synaptic interaction in the gastric CPG is reciprocal inhibition. A pair of identical model cells, connected with reciprocal inhibition, oscillates in antiphase if either the isolated cells are endogenous oscillators, or they are quiescent without plateau potentials, or they have plateau potentials but the synaptic strengths are below a critical level. If the isolated cells have widely differing frequencies (or would have if the cells were made to oscillate by adjusting the fast currents), reciprocal inhibition entrains the cells to oscillate with the same frequency but with phases that are advanced or retarded relative to the phases seen when the cells have the same frequency. The frequency of the entrained pair of cells lies between the frequencies of the original cells. The relative phases can also be modified by using very unequal synaptic strengths.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
• W753599254 created "2016-06-24" @default.
• W753599254 creator A5071194990 @default.
• W753599254 creator A5089423451 @default.
• W753599254 date "1993-09-01" @default.
• W753599254 modified "2023-09-27" @default.
• W753599254 title "Modeling the gastric mill central pattern generator of the lobster with a relaxation-oscillator network" @default.
• W753599254 cites W1530931050 @default.
• W753599254 cites W159676655 @default.
• W753599254 cites W1956090594 @default.
• W753599254 cites W1967385769 @default.
• W753599254 cites W2007100504 @default.
• W753599254 cites W2012546758 @default.
• W753599254 cites W2016589492 @default.
• W753599254 cites W2021973929 @default.
• W753599254 cites W2028445032 @default.
• W753599254 cites W2033052427 @default.
• W753599254 cites W2039964124 @default.
• W753599254 cites W2041664896 @default.
• W753599254 cites W2044172180 @default.
• W753599254 cites W2072389568 @default.
• W753599254 cites W2072630662 @default.
• W753599254 cites W2074911271 @default.
• W753599254 cites W2078794407 @default.
• W753599254 cites W2089876099 @default.
• W753599254 cites W2093469113 @default.
• W753599254 cites W2098186057 @default.
• W753599254 cites W2119301498 @default.
• W753599254 cites W2133000560 @default.
• W753599254 cites W2157452599 @default.
• W753599254 cites W2162986451 @default.
• W753599254 cites W2166008444 @default.
• W753599254 cites W2219473100 @default.
• W753599254 cites W2275727258 @default.
• W753599254 cites W2414372201 @default.
• W753599254 cites W2433931587 @default.
• W753599254 cites W3009484639 @default.
• W753599254 cites W44817667 @default.
• W753599254 cites W81727061 @default.
• W753599254 cites W2441732695 @default.
• W753599254 doi "https://doi.org/10.1152/jn.1993.70.3.1030" @default.
• W753599254 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8229158" @default.
• W753599254 hasPublicationYear "1993" @default.
• W753599254 type Work @default.
• W753599254 sameAs 753599254 @default.
• W753599254 citedByCount "81" @default.
• W753599254 countsByYear W7535992542012 @default.
• W753599254 countsByYear W7535992542013 @default.
• W753599254 countsByYear W7535992542014 @default.
• W753599254 countsByYear W7535992542015 @default.
• W753599254 countsByYear W7535992542016 @default.
• W753599254 countsByYear W7535992542017 @default.
• W753599254 countsByYear W7535992542018 @default.
• W753599254 countsByYear W7535992542019 @default.
• W753599254 countsByYear W7535992542020 @default.
• W753599254 countsByYear W7535992542021 @default.
• W753599254 countsByYear W7535992542022 @default.
• W753599254 countsByYear W7535992542023 @default.
• W753599254 crossrefType "journal-article" @default.
• W753599254 hasAuthorship W753599254A5071194990 @default.
• W753599254 hasAuthorship W753599254A5089423451 @default.
• W753599254 hasConcept C121332964 @default.
• W753599254 hasConcept C135343436 @default.
• W753599254 hasConcept C147944092 @default.
• W753599254 hasConcept C148043351 @default.
• W753599254 hasConcept C154945302 @default.
• W753599254 hasConcept C163258240 @default.
• W753599254 hasConcept C169453685 @default.
• W753599254 hasConcept C169760540 @default.
• W753599254 hasConcept C181911157 @default.
• W753599254 hasConcept C185263204 @default.
• W753599254 hasConcept C186060115 @default.
• W753599254 hasConcept C24890656 @default.
• W753599254 hasConcept C2775924081 @default.
• W753599254 hasConcept C2778071365 @default.
• W753599254 hasConcept C2778794669 @default.
• W753599254 hasConcept C2780992000 @default.
• W753599254 hasConcept C41008148 @default.
• W753599254 hasConcept C47446073 @default.
• W753599254 hasConcept C57879066 @default.
• W753599254 hasConcept C62520636 @default.
• W753599254 hasConcept C86803240 @default.
• W753599254 hasConcept C97355855 @default.
• W753599254 hasConceptScore W753599254C121332964 @default.
• W753599254 hasConceptScore W753599254C135343436 @default.
• W753599254 hasConceptScore W753599254C147944092 @default.
• W753599254 hasConceptScore W753599254C148043351 @default.
• W753599254 hasConceptScore W753599254C154945302 @default.
• W753599254 hasConceptScore W753599254C163258240 @default.
• W753599254 hasConceptScore W753599254C169453685 @default.
• W753599254 hasConceptScore W753599254C169760540 @default.
• W753599254 hasConceptScore W753599254C181911157 @default.
• W753599254 hasConceptScore W753599254C185263204 @default.
• W753599254 hasConceptScore W753599254C186060115 @default.
• W753599254 hasConceptScore W753599254C24890656 @default.
• W753599254 hasConceptScore W753599254C2775924081 @default.
• W753599254 hasConceptScore W753599254C2778071365 @default.
• W753599254 hasConceptScore W753599254C2778794669 @default.

• next