FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W75375952> ?p ?o ?g. }

• W75375952 abstract "Background and Aims: Although numerous studies have evaluated outcomes pertaining to endoscopic retrograde cholangio-pancreatography (ERCP) complications, studies evaluating outcomes of management of post-ERCP pancreatitis are scant. This study evaluated the effectiveness of a standard treatment protocol in management of post-ERCP pancreatitis. Methods: This is a retrospective study of consecutive patients managed for post-ERCP pancreatitis, using a standard treatment protocol over a 3-year period. By protocol, patients received only intravenous fluids, narcotics, and analgesics for the first 24-72 h after admission. Oral intake was attempted when white cell count was normal or followed a downward trend, abdominal pain was absent or minimal without need for narcotics over a 12-h period, and serum lipase was less than three times normal range. For patients hospitalized beyond 72 h, an abdomen CT was obtained at days 4 and 10 to guide management. Intravenous antibiotics were administered only for patients with pancreatic necrosis. Jejunal feeding and a meperidine pump for pain control were initiated in symptomatic patients at day 4. Data on ERCP complications were collected prospectively and graded per consensus criteria. Effectiveness of the treatment protocol was evaluated by comparing clinical outcomes of patients managed by protocol versus those managed outside protocol. Results: 45 of 1976 patients (2.3%) who underwent ERCP developed post-ERCP pancreatitis. Of the 45 (female 31; mean age 43 years) patients, 32 were managed by protocol and 13 outside protocol. Protocol based management was associated with less severe disease as compared with those managed outside protocol (crude odds ratio (OR) = 11.2; 95% confidence interval (CI) = 1.9-68.7; P = 0.002). One patient managed outside protocol died of severe pancreatitis. When compared with those managed outside protocol, the median duration of hospital stay (7 vs 3 days; P = 0.01), the use of CT (100% vs 15.6%; P < 0.001), and the use of antibiotics (50% vs 3.1%; P=0.01) were significantly lower in those managed by protocol. By multiple logistic regression, protocol-based management was associated with less severe disease (adjusted OR = 18.7; 95% CI = 2.6-132.1; P = 0.003) when adjusted for age, comorbidity, endotherapy and pancreatic stenting. Conclusions: A protocol-based management strategy was associated with less severe pancreatitis, shorter length of hospital stay, need for fewer imaging studies, and use of antibiotics. Prospective validation of these findings is justified." @default.
• W75375952 created "2016-06-24" @default.
• W75375952 creator A5002904973 @default.
• W75375952 creator A5004311331 @default.
• W75375952 creator A5031396930 @default.
• W75375952 creator A5040435359 @default.
• W75375952 creator A5045645161 @default.
• W75375952 creator A5056852307 @default.
• W75375952 creator A5063858151 @default.
• W75375952 creator A5069563248 @default.
• W75375952 date "2008-01-01" @default.
• W75375952 modified "2023-09-22" @default.
• W75375952 title "Protocol-based medical management of post-ERCP pancreatitis. Commentary" @default.
• W75375952 hasPublicationYear "2008" @default.
• W75375952 type Work @default.
• W75375952 sameAs 75375952 @default.
• W75375952 citedByCount "0" @default.
• W75375952 crossrefType "journal-article" @default.
• W75375952 hasAuthorship W75375952A5002904973 @default.
• W75375952 hasAuthorship W75375952A5004311331 @default.
• W75375952 hasAuthorship W75375952A5031396930 @default.
• W75375952 hasAuthorship W75375952A5040435359 @default.
• W75375952 hasAuthorship W75375952A5045645161 @default.
• W75375952 hasAuthorship W75375952A5056852307 @default.
• W75375952 hasAuthorship W75375952A5063858151 @default.
• W75375952 hasAuthorship W75375952A5069563248 @default.
• W75375952 hasConcept C126322002 @default.
• W75375952 hasConcept C141071460 @default.
• W75375952 hasConcept C142724271 @default.
• W75375952 hasConcept C156957248 @default.
• W75375952 hasConcept C167135981 @default.
• W75375952 hasConcept C204787440 @default.
• W75375952 hasConcept C2775967933 @default.
• W75375952 hasConcept C2776670229 @default.
• W75375952 hasConcept C2776737053 @default.
• W75375952 hasConcept C2778764654 @default.
• W75375952 hasConcept C2780385302 @default.
• W75375952 hasConcept C2780955771 @default.
• W75375952 hasConcept C71924100 @default.
• W75375952 hasConceptScore W75375952C126322002 @default.
• W75375952 hasConceptScore W75375952C141071460 @default.
• W75375952 hasConceptScore W75375952C142724271 @default.
• W75375952 hasConceptScore W75375952C156957248 @default.
• W75375952 hasConceptScore W75375952C167135981 @default.
• W75375952 hasConceptScore W75375952C204787440 @default.
• W75375952 hasConceptScore W75375952C2775967933 @default.
• W75375952 hasConceptScore W75375952C2776670229 @default.
• W75375952 hasConceptScore W75375952C2776737053 @default.
• W75375952 hasConceptScore W75375952C2778764654 @default.
• W75375952 hasConceptScore W75375952C2780385302 @default.
• W75375952 hasConceptScore W75375952C2780955771 @default.
• W75375952 hasConceptScore W75375952C71924100 @default.
• W75375952 hasIssue "3" @default.
• W75375952 hasLocation W753759521 @default.
• W75375952 hasOpenAccess W75375952 @default.
• W75375952 hasPrimaryLocation W753759521 @default.
• W75375952 hasRelatedWork W2019116259 @default.
• W75375952 hasRelatedWork W2026144520 @default.
• W75375952 hasRelatedWork W2034153914 @default.
• W75375952 hasRelatedWork W2051094013 @default.
• W75375952 hasRelatedWork W2056211981 @default.
• W75375952 hasRelatedWork W2063797513 @default.
• W75375952 hasRelatedWork W2082855317 @default.
• W75375952 hasRelatedWork W2130766183 @default.
• W75375952 hasRelatedWork W2131105149 @default.
• W75375952 hasRelatedWork W2354309484 @default.
• W75375952 hasRelatedWork W2374561240 @default.
• W75375952 hasRelatedWork W2607944130 @default.
• W75375952 hasRelatedWork W2742358737 @default.
• W75375952 hasRelatedWork W2908733389 @default.
• W75375952 hasRelatedWork W3013926168 @default.
• W75375952 hasRelatedWork W3030155257 @default.
• W75375952 hasRelatedWork W3030158093 @default.
• W75375952 hasRelatedWork W3031235175 @default.
• W75375952 hasRelatedWork W3209567411 @default.
• W75375952 hasRelatedWork W3210992569 @default.
• W75375952 hasVolume "23" @default.
• W75375952 isParatext "false" @default.
• W75375952 isRetracted "false" @default.
• W75375952 magId "75375952" @default.
• W75375952 workType "article" @default.