Matches in SemOpenAlex for { <https://semopenalex.org/work/W75429502> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W75429502 endingPage "228" @default.
- W75429502 startingPage "215" @default.
- W75429502 abstract "This chapter discusses chemical synthesis for the understanding of immune response phenomena and for their medical application. The synthetic branched polymer (T,G)-A–L is prepared by polymeric techniques throughout, that is, the specific determinants of this immunogen are prepared from multichain poly(DL-alanine) (A–L), serving as a polyvalent initiator for the polymerization of N-carboxyanhydrides of tyrosine and glutamic acid that are still reversibly blocked in their reactive functions. After deblocking, the final product contains chains of tyrosine and glutamic acid that can differ in the ratio of the two amino acids, in the length of the peptides, as well as in the precise amino acid sequence. A minimal change—the inversion of the sequence of the two interior amino acid residues within the tetrapeptide that serves as the antigenic determinant—causes a series of major differences in the biological properties of the immunogens of which they represent the major building blocks. These properties include the genetic control of immune responsiveness and the need for cell cooperation to mount an efficient immune response." @default.
- W75429502 created "2016-06-24" @default.
- W75429502 creator A5016902113 @default.
- W75429502 date "1980-01-01" @default.
- W75429502 modified "2023-10-18" @default.
- W75429502 title "CHEMICAL SYNTHESIS FOR THE UNDERSTANDING OF IMMUNE RESPONSE PHENOMENA AND FOR THEIR MEDICAL APPLICATION" @default.
- W75429502 cites W1020666978 @default.
- W75429502 cites W1417104882 @default.
- W75429502 cites W1597280377 @default.
- W75429502 cites W1971067549 @default.
- W75429502 cites W1971213733 @default.
- W75429502 cites W1977069525 @default.
- W75429502 cites W1982497030 @default.
- W75429502 cites W1986438054 @default.
- W75429502 cites W1989416163 @default.
- W75429502 cites W2007055191 @default.
- W75429502 cites W2021120426 @default.
- W75429502 cites W2022248021 @default.
- W75429502 cites W2027716480 @default.
- W75429502 cites W203083881 @default.
- W75429502 cites W2034735571 @default.
- W75429502 cites W2038722446 @default.
- W75429502 cites W2042823571 @default.
- W75429502 cites W2060900298 @default.
- W75429502 cites W2076309853 @default.
- W75429502 cites W2082785802 @default.
- W75429502 cites W2095428136 @default.
- W75429502 cites W2104377381 @default.
- W75429502 cites W2114804450 @default.
- W75429502 cites W2152820466 @default.
- W75429502 cites W2165382099 @default.
- W75429502 cites W2413045917 @default.
- W75429502 cites W4313307174 @default.
- W75429502 doi "https://doi.org/10.1016/b978-0-12-436840-8.50022-2" @default.
- W75429502 hasPublicationYear "1980" @default.
- W75429502 type Work @default.
- W75429502 sameAs 75429502 @default.
- W75429502 citedByCount "6" @default.
- W75429502 crossrefType "book-chapter" @default.
- W75429502 hasAuthorship W75429502A5016902113 @default.
- W75429502 hasConcept C159654299 @default.
- W75429502 hasConcept C178790620 @default.
- W75429502 hasConcept C185592680 @default.
- W75429502 hasConcept C203014093 @default.
- W75429502 hasConcept C21951064 @default.
- W75429502 hasConcept C2776165026 @default.
- W75429502 hasConcept C2778740566 @default.
- W75429502 hasConcept C2779281246 @default.
- W75429502 hasConcept C2779564779 @default.
- W75429502 hasConcept C2779856020 @default.
- W75429502 hasConcept C2779909307 @default.
- W75429502 hasConcept C44228677 @default.
- W75429502 hasConcept C515207424 @default.
- W75429502 hasConcept C521977710 @default.
- W75429502 hasConcept C542903549 @default.
- W75429502 hasConcept C55493867 @default.
- W75429502 hasConcept C71240020 @default.
- W75429502 hasConcept C86803240 @default.
- W75429502 hasConcept C8891405 @default.
- W75429502 hasConceptScore W75429502C159654299 @default.
- W75429502 hasConceptScore W75429502C178790620 @default.
- W75429502 hasConceptScore W75429502C185592680 @default.
- W75429502 hasConceptScore W75429502C203014093 @default.
- W75429502 hasConceptScore W75429502C21951064 @default.
- W75429502 hasConceptScore W75429502C2776165026 @default.
- W75429502 hasConceptScore W75429502C2778740566 @default.
- W75429502 hasConceptScore W75429502C2779281246 @default.
- W75429502 hasConceptScore W75429502C2779564779 @default.
- W75429502 hasConceptScore W75429502C2779856020 @default.
- W75429502 hasConceptScore W75429502C2779909307 @default.
- W75429502 hasConceptScore W75429502C44228677 @default.
- W75429502 hasConceptScore W75429502C515207424 @default.
- W75429502 hasConceptScore W75429502C521977710 @default.
- W75429502 hasConceptScore W75429502C542903549 @default.
- W75429502 hasConceptScore W75429502C55493867 @default.
- W75429502 hasConceptScore W75429502C71240020 @default.
- W75429502 hasConceptScore W75429502C86803240 @default.
- W75429502 hasConceptScore W75429502C8891405 @default.
- W75429502 hasLocation W754295021 @default.
- W75429502 hasOpenAccess W75429502 @default.
- W75429502 hasPrimaryLocation W754295021 @default.
- W75429502 hasRelatedWork W1487965268 @default.
- W75429502 hasRelatedWork W1963757155 @default.
- W75429502 hasRelatedWork W2026191709 @default.
- W75429502 hasRelatedWork W2149249683 @default.
- W75429502 hasRelatedWork W2150367211 @default.
- W75429502 hasRelatedWork W2281211411 @default.
- W75429502 hasRelatedWork W2350755399 @default.
- W75429502 hasRelatedWork W317694659 @default.
- W75429502 hasRelatedWork W4316664160 @default.
- W75429502 hasRelatedWork W75429502 @default.
- W75429502 isParatext "false" @default.
- W75429502 isRetracted "false" @default.
- W75429502 magId "75429502" @default.
- W75429502 workType "book-chapter" @default.