Matches in SemOpenAlex for { <https://semopenalex.org/work/W754882019> ?p ?o ?g. }
- W754882019 endingPage "346" @default.
- W754882019 startingPage "339" @default.
- W754882019 abstract "The interaction of hepatitis B drug, adefovir dipivoxil with human serum albumin (HSA) was studied by using UV–vis, fluorometric, circular dichroism (CD) and molecular docking techniques. The results indicated that the binding of the drug to HSA caused fluorescence quenching through static quenching mechanism with binding constant of 1.3×103 M−1. The thermodynamic parameters indicated that the hydrophobic force contacts are the major forces in the stability of protein-drug complex (ΔH>0 and ΔS>0). The displacement experiments using the site probes viz., warfarin and ibuprofen showed that adefovir dipivoxil could bind to the site III of HSA. The results of CD and UV–vis spectroscopy indicated that the binding of the drug induced some conformational changes in HSA. Furthermore, the study of molecular docking also confirmed binding of adefovir dipivoxil to the site III of HSA by hydrophobic interaction." @default.
- W754882019 created "2016-06-24" @default.
- W754882019 creator A5017588599 @default.
- W754882019 creator A5068670190 @default.
- W754882019 creator A5084326896 @default.
- W754882019 date "2015-11-01" @default.
- W754882019 modified "2023-10-06" @default.
- W754882019 title "Molecular modeling and multispectroscopic studies of the interaction of hepatitis B drug, adefovir dipivoxil with human serum albumin" @default.
- W754882019 cites W1504792186 @default.
- W754882019 cites W1964923410 @default.
- W754882019 cites W1981883043 @default.
- W754882019 cites W1983626948 @default.
- W754882019 cites W1984163168 @default.
- W754882019 cites W1992919643 @default.
- W754882019 cites W2000499948 @default.
- W754882019 cites W2004006450 @default.
- W754882019 cites W2008166117 @default.
- W754882019 cites W2008316253 @default.
- W754882019 cites W2016401253 @default.
- W754882019 cites W2016473036 @default.
- W754882019 cites W2019312422 @default.
- W754882019 cites W2022294896 @default.
- W754882019 cites W2022520522 @default.
- W754882019 cites W2025131298 @default.
- W754882019 cites W2028689547 @default.
- W754882019 cites W2030802512 @default.
- W754882019 cites W2032718322 @default.
- W754882019 cites W2038627658 @default.
- W754882019 cites W2040252355 @default.
- W754882019 cites W2045150607 @default.
- W754882019 cites W2049080258 @default.
- W754882019 cites W2055744129 @default.
- W754882019 cites W2057444232 @default.
- W754882019 cites W2057705273 @default.
- W754882019 cites W2060578259 @default.
- W754882019 cites W2061832104 @default.
- W754882019 cites W2067041836 @default.
- W754882019 cites W2073798416 @default.
- W754882019 cites W2083142355 @default.
- W754882019 cites W2087067242 @default.
- W754882019 cites W2088103780 @default.
- W754882019 cites W2094500627 @default.
- W754882019 cites W2150645499 @default.
- W754882019 cites W2152604288 @default.
- W754882019 cites W2171557261 @default.
- W754882019 cites W2393327590 @default.
- W754882019 cites W4248758566 @default.
- W754882019 doi "https://doi.org/10.1016/j.jlumin.2015.07.006" @default.
- W754882019 hasPublicationYear "2015" @default.
- W754882019 type Work @default.
- W754882019 sameAs 754882019 @default.
- W754882019 citedByCount "12" @default.
- W754882019 countsByYear W7548820192016 @default.
- W754882019 countsByYear W7548820192017 @default.
- W754882019 countsByYear W7548820192018 @default.
- W754882019 countsByYear W7548820192019 @default.
- W754882019 countsByYear W7548820192020 @default.
- W754882019 countsByYear W7548820192021 @default.
- W754882019 crossrefType "journal-article" @default.
- W754882019 hasAuthorship W754882019A5017588599 @default.
- W754882019 hasAuthorship W754882019A5068670190 @default.
- W754882019 hasAuthorship W754882019A5084326896 @default.
- W754882019 hasConcept C107824862 @default.
- W754882019 hasConcept C121332964 @default.
- W754882019 hasConcept C121745418 @default.
- W754882019 hasConcept C12554922 @default.
- W754882019 hasConcept C133571119 @default.
- W754882019 hasConcept C159047783 @default.
- W754882019 hasConcept C165616093 @default.
- W754882019 hasConcept C185592680 @default.
- W754882019 hasConcept C2522874641 @default.
- W754882019 hasConcept C2777869810 @default.
- W754882019 hasConcept C2778597219 @default.
- W754882019 hasConcept C2779517838 @default.
- W754882019 hasConcept C2780593183 @default.
- W754882019 hasConcept C32786932 @default.
- W754882019 hasConcept C55493867 @default.
- W754882019 hasConcept C62520636 @default.
- W754882019 hasConcept C62614982 @default.
- W754882019 hasConcept C71240020 @default.
- W754882019 hasConcept C86803240 @default.
- W754882019 hasConcept C90260826 @default.
- W754882019 hasConcept C91881484 @default.
- W754882019 hasConceptScore W754882019C107824862 @default.
- W754882019 hasConceptScore W754882019C121332964 @default.
- W754882019 hasConceptScore W754882019C121745418 @default.
- W754882019 hasConceptScore W754882019C12554922 @default.
- W754882019 hasConceptScore W754882019C133571119 @default.
- W754882019 hasConceptScore W754882019C159047783 @default.
- W754882019 hasConceptScore W754882019C165616093 @default.
- W754882019 hasConceptScore W754882019C185592680 @default.
- W754882019 hasConceptScore W754882019C2522874641 @default.
- W754882019 hasConceptScore W754882019C2777869810 @default.
- W754882019 hasConceptScore W754882019C2778597219 @default.
- W754882019 hasConceptScore W754882019C2779517838 @default.
- W754882019 hasConceptScore W754882019C2780593183 @default.
- W754882019 hasConceptScore W754882019C32786932 @default.
- W754882019 hasConceptScore W754882019C55493867 @default.