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• W755243570 abstract "Gamma irradiation at 5 kGy was applied to beefs for evaluation of their possible genotoxicity and acute oral toxicity. The genotoxicity of 5 kGy irradiated beef was evaluated by Salmonella typhimurium reversion assay and in vivo micronucleus assay using mouse bone marrow cells. The results were negative in the bacterial reversion assay with S. typhimurium TA98, TA100, TA1535, TA1537. Clastogenic effects were not shown in vivo mouse micronucleus assay at 5 kGy dose tested. In an acute toxicity test, 5 kGy-irradiated beef was administrated orally at a dose level of 313 to 5,000 mg/kg, and then number of deaths, clinical signs, body weights, and pathological examinations were examined daily for 14 days post-administration. The results indicate that 5 kGy irradiated beef did not show any toxic effect on mice and oral value was over 5,000 mg/kg on ICR mice." @default.
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• W755243570 date "1998-01-01" @default.
• W755243570 modified "2023-09-24" @default.
• W755243570 title "Genotoxicological and Acute Toxicological Safeties of Gamma Irradiated Beef" @default.
• W755243570 hasPublicationYear "1998" @default.
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