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- W758033410 abstract "Recent advances in the therapy of pediatric malignancy have improved the quality of life and the overall survival for children with hematologic or solid tumors. Children with malignancy may present with problems that immediately threaten vital organ function or long term quality of life, necessitating skilled emergency management. The primary care physician must stabilize the patient prior to initiation of specific anti-tumor therapy. Later, he must be prepared to recognize and treat the complications that arise from tumor recurrence or from the attendant complications of prolonged and aggressive courses of treatment. The increasing use of bone marrow transplantation has added new complications, including accentuation of chemotherapy toxicities from the supralethal doses used in conditioning regimens, more opportunistic infections, and graft versus host disease. All decisions pertaining to the critically ill oncology patient should be made with the overall treatment goals in mind. Knowledge of the underlying disease status, the patient–s nutritional state, any organ malfunction, and previous surgery, radiation and chemotherapy are all essential. The pediatric oncology patient may develop complications due either to tumor progression or to complications of treatment. This review will cover some of the common acute problems which cause respiratory, neurologic, metabolic, and hematologic emergencies (For rapid overview see references [1] and [2]; for general review see references [3–6].KeywordsUric AcidPediatric Intensive Care UnitBlast CellTumor Lysis SyndromeNephrogenic Diabetes InsipidusThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W758033410 date "1987-01-01" @default.
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- W758033410 title "Oncologic and Hematologic Problems in the Pediatric Intensive Care Unit" @default.
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- W758033410 doi "https://doi.org/10.1007/978-3-642-83042-6_60" @default.
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