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- W75863624 abstract "Object: The aim of this study is to evaluate thesociodemographic and clinical features and efficacy ofclozapine treatment in patients with bipolar disorder (BD) andschizoaffective disorder (SD).Method: Patients with DSM-IVdiagnostic criteria for BD and SD on clozapine treatment forat least one year and followed up regularly were included inthe study. We reviewed the patients' medical records andlife-charts retrospectively. To assess the functioning of thepatients, the Clinical Global Impression scale-A (CGI-A) andCGI-B and Global Assessment of Functioning (GAF) wereperformed preceding 3 months of clozapine treatment andcurrent status.Results: Of 36 patients on clozapinetreatment, 17 (46%) were diagnosed as BD and 19 (54%)were diagnosed as SD. The mean age of onset of illness was24.0±6.4 years. The current mean age of the group was40.8±9.0 years. Even though the mean duration of illness, themean age of onset of illness and the mean duration of illnessbefore clozapine treatment were not significantly differentbetween two groups, the mean daily dose and duration ofclozapine treatment were significantly higher in patients withSD than BD (p" @default.
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- W75863624 date "2002-01-01" @default.
- W75863624 modified "2023-09-28" @default.
- W75863624 title "Clozapine treatment in bipolar and schizoaffective disorders: A retrospective study" @default.
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