Matches in SemOpenAlex for { <https://semopenalex.org/work/W75954993> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W75954993 endingPage "4" @default.
- W75954993 startingPage "1" @default.
- W75954993 abstract "Detection, enumeration and characterization of rare circulating tumor cells (CTCs) from the peripheral blood of cancer patients potentially provide critical insights into tumor biology and is promising for cancer diagnosis and prognosis. Here, we present a novel multiplexed spiral microfluidic device for ultra-high throughput, label-free enrichment of CTCs from clinically relevant blood volumes. The fast processing time of the technique (7.5 mL blood in < 5 min) and high sensitivity of the device lends itself to a broad range of potential genomic and transcriptomic applications. The method can specifically separate and preserve all fractions of blood (i.e., plasma, CTCs and PBMC) for diverse downstream analysis. CTCs were detected from 100% (10/10) of blood samples collected from patients with advanced stage metastatic breast (12-56 CTC/ml) or lung cancer (30-153 CTC/ml). Cancer cells were characterized with immunostaining and fluorescence in situ hybridization (FISH) (HER2/neu). Retrieved cells were unlabelled and hence more viable for propagation and other informative analysis such as the next generation sequencing (NGS) to guide treatment and individualized patient care." @default.
- W75954993 created "2016-06-24" @default.
- W75954993 creator A5031891367 @default.
- W75954993 creator A5032293215 @default.
- W75954993 creator A5033700679 @default.
- W75954993 creator A5037394728 @default.
- W75954993 creator A5039828232 @default.
- W75954993 creator A5040724246 @default.
- W75954993 creator A5054147614 @default.
- W75954993 creator A5059269204 @default.
- W75954993 creator A5061589915 @default.
- W75954993 creator A5068940854 @default.
- W75954993 creator A5086823725 @default.
- W75954993 date "2014-01-01" @default.
- W75954993 modified "2023-10-18" @default.
- W75954993 title "Ultra-High Throughput Enrichment of Viable Circulating Tumor Cells" @default.
- W75954993 cites W1992421519 @default.
- W75954993 cites W2016121055 @default.
- W75954993 cites W2023427658 @default.
- W75954993 cites W2025214655 @default.
- W75954993 cites W2035869340 @default.
- W75954993 cites W2045200738 @default.
- W75954993 cites W2050547995 @default.
- W75954993 cites W2057142830 @default.
- W75954993 cites W2063140987 @default.
- W75954993 cites W2066419333 @default.
- W75954993 cites W2097950721 @default.
- W75954993 cites W2115158793 @default.
- W75954993 cites W2139799027 @default.
- W75954993 doi "https://doi.org/10.1007/978-3-319-02913-9_1" @default.
- W75954993 hasPublicationYear "2014" @default.
- W75954993 type Work @default.
- W75954993 sameAs 75954993 @default.
- W75954993 citedByCount "2" @default.
- W75954993 countsByYear W759549932014 @default.
- W75954993 countsByYear W759549932015 @default.
- W75954993 crossrefType "book-chapter" @default.
- W75954993 hasAuthorship W75954993A5031891367 @default.
- W75954993 hasAuthorship W75954993A5032293215 @default.
- W75954993 hasAuthorship W75954993A5033700679 @default.
- W75954993 hasAuthorship W75954993A5037394728 @default.
- W75954993 hasAuthorship W75954993A5039828232 @default.
- W75954993 hasAuthorship W75954993A5040724246 @default.
- W75954993 hasAuthorship W75954993A5054147614 @default.
- W75954993 hasAuthorship W75954993A5059269204 @default.
- W75954993 hasAuthorship W75954993A5061589915 @default.
- W75954993 hasAuthorship W75954993A5068940854 @default.
- W75954993 hasAuthorship W75954993A5086823725 @default.
- W75954993 hasConcept C111919701 @default.
- W75954993 hasConcept C121608353 @default.
- W75954993 hasConcept C157764524 @default.
- W75954993 hasConcept C185592680 @default.
- W75954993 hasConcept C2779013556 @default.
- W75954993 hasConcept C41008148 @default.
- W75954993 hasConcept C502942594 @default.
- W75954993 hasConcept C54355233 @default.
- W75954993 hasConcept C555944384 @default.
- W75954993 hasConcept C61238886 @default.
- W75954993 hasConcept C70721500 @default.
- W75954993 hasConcept C86803240 @default.
- W75954993 hasConceptScore W75954993C111919701 @default.
- W75954993 hasConceptScore W75954993C121608353 @default.
- W75954993 hasConceptScore W75954993C157764524 @default.
- W75954993 hasConceptScore W75954993C185592680 @default.
- W75954993 hasConceptScore W75954993C2779013556 @default.
- W75954993 hasConceptScore W75954993C41008148 @default.
- W75954993 hasConceptScore W75954993C502942594 @default.
- W75954993 hasConceptScore W75954993C54355233 @default.
- W75954993 hasConceptScore W75954993C555944384 @default.
- W75954993 hasConceptScore W75954993C61238886 @default.
- W75954993 hasConceptScore W75954993C70721500 @default.
- W75954993 hasConceptScore W75954993C86803240 @default.
- W75954993 hasLocation W759549931 @default.
- W75954993 hasOpenAccess W75954993 @default.
- W75954993 hasPrimaryLocation W759549931 @default.
- W75954993 hasRelatedWork W1002902646 @default.
- W75954993 hasRelatedWork W160116885 @default.
- W75954993 hasRelatedWork W2011083790 @default.
- W75954993 hasRelatedWork W2059929079 @default.
- W75954993 hasRelatedWork W2381241007 @default.
- W75954993 hasRelatedWork W2526884355 @default.
- W75954993 hasRelatedWork W2621281690 @default.
- W75954993 hasRelatedWork W2625512991 @default.
- W75954993 hasRelatedWork W2748952813 @default.
- W75954993 hasRelatedWork W2899084033 @default.
- W75954993 isParatext "false" @default.
- W75954993 isRetracted "false" @default.
- W75954993 magId "75954993" @default.
- W75954993 workType "book-chapter" @default.