Matches in SemOpenAlex for { <https://semopenalex.org/work/W75998957> ?p ?o ?g. }
- W75998957 endingPage "142" @default.
- W75998957 startingPage "127" @default.
- W75998957 abstract "While speculation has centered on a role for nuclear lamins in tumor progression for many years, most of the diseases that have been linked to lamin mutation are dystrophic in nature, often limiting the proliferation potential of affected cells in vivo and in vitro. Nevertheless, these lamin mutations, particularly in the LMNA gene that encodes A-type lamins, have provided an interesting tool set to understand functions of nuclear intermediate filament proteins in cell cycle progress and various means of exit, including quiescence, senescence, and differentiation down various lineages. The picture that has emerged is complex with lamins controlling the activity of key cell cycle factors such as the retinoblastoma protein (RB) and interacting with several important signal transduction pathways. Here we describe the current state of knowledge and speculate that lamins may be intimately involved in the regulation of cell proliferation, acting at the interface between cancer and aging." @default.
- W75998957 created "2016-06-24" @default.
- W75998957 creator A5009940609 @default.
- W75998957 creator A5013113087 @default.
- W75998957 date "2014-01-01" @default.
- W75998957 modified "2023-10-18" @default.
- W75998957 title "RB and Lamins in Cell Cycle Regulation and Aging" @default.
- W75998957 cites W1486122524 @default.
- W75998957 cites W1582605856 @default.
- W75998957 cites W1622556758 @default.
- W75998957 cites W1820443931 @default.
- W75998957 cites W1825795866 @default.
- W75998957 cites W1964551999 @default.
- W75998957 cites W1965376405 @default.
- W75998957 cites W1965880146 @default.
- W75998957 cites W1974449792 @default.
- W75998957 cites W1984775769 @default.
- W75998957 cites W1985465304 @default.
- W75998957 cites W1986960362 @default.
- W75998957 cites W1988510960 @default.
- W75998957 cites W1994167061 @default.
- W75998957 cites W1996962517 @default.
- W75998957 cites W1997662116 @default.
- W75998957 cites W1998663807 @default.
- W75998957 cites W2000320650 @default.
- W75998957 cites W2002569327 @default.
- W75998957 cites W2008620234 @default.
- W75998957 cites W2008900071 @default.
- W75998957 cites W2009306385 @default.
- W75998957 cites W2010399610 @default.
- W75998957 cites W2015467784 @default.
- W75998957 cites W2017870541 @default.
- W75998957 cites W2017985097 @default.
- W75998957 cites W2021302591 @default.
- W75998957 cites W2022633326 @default.
- W75998957 cites W2023314817 @default.
- W75998957 cites W2024065774 @default.
- W75998957 cites W2024859225 @default.
- W75998957 cites W2040002798 @default.
- W75998957 cites W2043928816 @default.
- W75998957 cites W2044051238 @default.
- W75998957 cites W2045856411 @default.
- W75998957 cites W2048839498 @default.
- W75998957 cites W2050838528 @default.
- W75998957 cites W2052011655 @default.
- W75998957 cites W2053206914 @default.
- W75998957 cites W2060311056 @default.
- W75998957 cites W2061843169 @default.
- W75998957 cites W2065520618 @default.
- W75998957 cites W2066442023 @default.
- W75998957 cites W2070106501 @default.
- W75998957 cites W2072810104 @default.
- W75998957 cites W2073224213 @default.
- W75998957 cites W2073610802 @default.
- W75998957 cites W2081589969 @default.
- W75998957 cites W2082182268 @default.
- W75998957 cites W2082186299 @default.
- W75998957 cites W2085216724 @default.
- W75998957 cites W2085683753 @default.
- W75998957 cites W2089681960 @default.
- W75998957 cites W2096262820 @default.
- W75998957 cites W2096354772 @default.
- W75998957 cites W2097265055 @default.
- W75998957 cites W2099742439 @default.
- W75998957 cites W2099805059 @default.
- W75998957 cites W2107549899 @default.
- W75998957 cites W2108757615 @default.
- W75998957 cites W2110961437 @default.
- W75998957 cites W2111622763 @default.
- W75998957 cites W2111986594 @default.
- W75998957 cites W2119932131 @default.
- W75998957 cites W2122983246 @default.
- W75998957 cites W2127365302 @default.
- W75998957 cites W2128353741 @default.
- W75998957 cites W2130024105 @default.
- W75998957 cites W2131593425 @default.
- W75998957 cites W2133139078 @default.
- W75998957 cites W2135564059 @default.
- W75998957 cites W2136420353 @default.
- W75998957 cites W2136490523 @default.
- W75998957 cites W2136835005 @default.
- W75998957 cites W2138591519 @default.
- W75998957 cites W2139893790 @default.
- W75998957 cites W2141153332 @default.
- W75998957 cites W2143185290 @default.
- W75998957 cites W2145283260 @default.
- W75998957 cites W2150748567 @default.
- W75998957 cites W2150987837 @default.
- W75998957 cites W2154140726 @default.
- W75998957 cites W2156812533 @default.
- W75998957 cites W2160703969 @default.
- W75998957 cites W2161183147 @default.
- W75998957 cites W2169643859 @default.
- W75998957 cites W2315512556 @default.
- W75998957 cites W2411028245 @default.
- W75998957 cites W4239880955 @default.
- W75998957 doi "https://doi.org/10.1007/978-1-4899-8032-8_6" @default.
- W75998957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24563346" @default.