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- W76084510 abstract "Publisher Summary In some tissues, the same biological end response can be mediated by basic type—either α or β—receptor. This apparent redundancy on the part of nature may have survival values: α and β adrenergic receptors usually activate different biochemical pathways with different metabolic consequences, and a change in their relative contribution to the final tissue response may serve to adapt tissue function to metabolic state. This chapter presents some observations of the authors of the chapter on the modulation of cardiac adrenoceptors by thyroid hormones. In an organ where the same end response to a hormone is mediated by two different receptors, some predictions can be made as to what type of changes in drug effects are expected if the relative numbers of the two receptors, in this case α and β, is altered. The chapter also discusses some of the recent findings of the author that indicate an interesting interaction between thyroid hormones and sympathetic innervation in the regulation of postsynaptic cardiac adrenoceptors." @default.
- W76084510 created "2016-06-24" @default.
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- W76084510 date "1981-01-01" @default.
- W76084510 modified "2023-09-27" @default.
- W76084510 title "INVERSE RECIPROCAL REGULATION OF CARDIAC POST-SYNAPTIC α- AND β- ADRENOCEPTORS BY THYROID HORMONES" @default.
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- W76084510 doi "https://doi.org/10.1016/b978-0-08-027348-8.50010-x" @default.
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