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- W76224243 abstract "The diverse molecular structure of drugs allows for numerous degradation pathways such as hydrolysis, oxidation, isomerization, photodegradation, polymerization, and elimination. Frequently, it is possible to predict chemical stability of drugs from the molecular structure. Good knowledge of the structure-stability relationship can be useful for stability prediction and to identify potential stability issues early during drug formulation. This chapter contains brief descriptions of the main drug degradation pathways with some examples with emphasis on theoretical interpretation of observed rate constants." @default.
- W76224243 created "2016-06-24" @default.
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- W76224243 date "2014-01-01" @default.
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- W76224243 title "Degradation Pathways" @default.
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- W76224243 doi "https://doi.org/10.1016/b978-0-12-411548-4.00003-9" @default.
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