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- W76410010 endingPage "680" @default.
- W76410010 startingPage "649" @default.
- W76410010 abstract "Publisher Summary Genome sequences are available for several common laboratory strains of haloarchaea. The genomes of these haloarchaea are relatively GC-rich (58–68%) and contain large and small extra chromosomal elements. Haloarchaea represent excellent experimental models for the studies of archaeal, extremophilic, and aspects of eukaryotic biology, such as DNA replication and transcription. Halobacterium sp. NRC-1 and Hfx. volcanii represent excellent systems for traditional genetic as well as genomic studies. The availability of the complete genome sequence for Halobacterium sp. NRC-1 , since 2000, has allowed significant advances in the development of postgenomic methodology of this organism. The extra chromosomal replicons are rich in IS elements and rearrange at high frequency. This is in contrast to their chromosomes, which are quite stable, and in fact contain a smaller number of transposable IS elements than some other archaea, e.g. Sulfolobus solfataricus. The combination of easy culturing, highly developed genetic and genomic tools, as well as interesting biology, makes haloarchaeal systems attractive for study. With the recent availability of complete genome sequences, systematic knockout strategies, DNA microarrays, and proteomic approaches, haloarchaeal model systems now have the potential for greatly advancing microbiology, molecular biology, and biotechnology." @default.
- W76410010 created "2016-06-24" @default.
- W76410010 creator A5026657416 @default.
- W76410010 creator A5031584276 @default.
- W76410010 creator A5046109896 @default.
- W76410010 date "2006-01-01" @default.
- W76410010 modified "2023-10-17" @default.
- W76410010 title "27 Genetic Systems for Halophilic Archaea" @default.
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