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• W76496417 abstract "The choice of empirical treatment for community-acquired pneumonia (CAP) is highly controversial. Our survey of 42 Australian emergency department doctors showed that monotherapy with a third-generation cephalosporin was the preferred regimen for severe CAP (14/42; 33%). We argue that cheaper regimens with a narrower spectrum are likely to be just as effective as third-generation cephalosporins and will have fewer adverse effects on the microbial ecology of hospitals. We suggest penicillin or ampicillin (to cover pneumococci - even if penicillin “resistant” - and Haemophilus influenzae), plus a macrolide (eg, azithromycin or erythromycin; to cover Legionella and other “atypical” pathogens), plus a single large dose of an aminoglycoside (eg, gentamicin; to cover gram-negative bacilli such as Klebsiella pneumoniae) as empirical therapy for severe CAP." @default.
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• W76496417 date "1998-04-01" @default.
• W76496417 modified "2023-09-25" @default.
• W76496417 title "Should third‐generation cephalosporins be the empirical treatment of choice for severe community‐acquired pneumonia in adults?" @default.
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• W76496417 doi "https://doi.org/10.5694/j.1326-5377.1998.tb138964.x" @default.
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