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- W765174234 abstract "This paper aims at analysis of clinical and epizootological features of manifestation and pathomorphological of a newly emerges and insufficiently studied disease in swine younglings, lawsoniosis. The disease is caused by Lawsonia intracelluaris, a gram-negative intracellular bacterium. The parasite resides inside cell which makes it hard to get to with antimicrobial preparations. Once ingested by an susceptible animal, Lawsonia penetrates inside the cells of inner intestinal lining, predominantly in the small intestine, where it reproduces itself. Infested cells are being exhausted and die. The bowel loses absorption capacity. Diarrhea syndrome leads to red blood cells loss and anemia. Activation of lawosoniosis agents is associated with feeding ration changes or when new production groups are formed. Disease occurrence rate increases after vaccination too. All these activities are associated with pronounced stress impact which changes intestinal microbiocenosis and affects animal’s natural resistance. Infected piglets grow behind healthy peers. They have rapidly deteriorating appearance with pale skin. Along with diarrhea development, feces become red and black with objectionable odor. The black coloration is caused by intestinal bleeding. Small bowel is mostly affected. Ileum mucous layer is thickened unevenly, has loose consistency with sparse hyperemic spots, dark red in color with hemorrhages. In most cases there are serosanguineous infiltrates along the entire length of ileum and small bowel. Taking into account physiologic mechanisms of the disease and in seek of an effective therapy alternative to antibiotics, we tested a complex immune metabolic preparation with anti-infective preparation Metallosuccinate (Patent RF 2351323). The preparation decreases diarrhea syndrome in 30 60 minutes. It took three sets of the preparation administration with interval of 24 hours to attain complete clinical recovery." @default.
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- W765174234 date "2015-01-01" @default.
- W765174234 modified "2023-09-23" @default.
- W765174234 title "Лавсониоз свиней: эпизоотологические и клинические особенности, вопросы диагностики, профилактики и лечения" @default.
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