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- W76519882 abstract "We present a comparative study between LC/MALDI/MS/MS and LC/ESI/MS/MS. Diagnostic biomarkers in saliva have beenidentified for monitoring caries, periodontitis, oral cancer, salivary gland diseases, and systemic disorders e.g.hepatitis and HIV[1]. Saliva is similar to serum in that there are a small number of highly abundant proteins and many low abundance proteins. There are 35 previously identified salivary proteins [1-4]. We prepared a representative sample of cysteine containing peptides and oxidised them to improve their fragmentation under MALDI conditions. In total 20 proteins were identified with 6been identified by both methods. Surprisingly there was little overlap in the peptides used to identify the proteinsbetween the two methods" @default.
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- W76519882 date "2005-06-05" @default.
- W76519882 modified "2023-09-27" @default.
- W76519882 title "A preliminary comparative analysis of the H. sapiens saliva proteome between cysteine fractionation,performic acid oxidation LC/MALDI/MS/MS and LC/ESI/MS/MS" @default.
- W76519882 hasPublicationYear "2005" @default.
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