Matches in SemOpenAlex for { <https://semopenalex.org/work/W766230837> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W766230837 endingPage "308" @default.
- W766230837 startingPage "306" @default.
- W766230837 abstract "目的:探讨β-catenin(p连环素)在大肠癌的表达及其与癌基因eyelinDl和C-myc的关系.方法:应用免疫组化PowervisionTM二步法,检测25名正常人大肠黏膜,42例大肠腺瘤和58例大肠癌组织β-catenin,cyclinDl和C-myc的表达情况.结果:正常大肠黏膜β-catenin胞膜阳性表达,cyclinDl和C-myc阴性.大肠腺瘤和大肠癌组织β-catenin呈胞质和/或胞核异位表达,大肠癌异位表达率为65.5%,显著高于大肠腺瘤(42.9%,P＜0.05).大肠癌cycbnDl和C-myc阳性率分别为74.1%、70.7%,均显著高于大肠腺瘤(45.2%,33.3%;P均＜0.01).大肠癌中pcatenin与cycunDl和C-myc表达呈明显正相关(r=0.32,O.57;P＜O.05,P＜0.01).结论:β-catenin异位表达可能是原癌基因cyclinDl和C-myc激活的原因之一,并在大肠癌发生过程中可能起重要作用." @default.
- W766230837 created "2016-06-24" @default.
- W766230837 creator A5005936582 @default.
- W766230837 creator A5008690145 @default.
- W766230837 creator A5029792261 @default.
- W766230837 creator A5089698306 @default.
- W766230837 date "2002-01-01" @default.
- W766230837 modified "2023-09-24" @default.
- W766230837 title "β—catenin,cyclin D1和c—myc在大肠癌组织中的表达" @default.
- W766230837 hasPublicationYear "2002" @default.
- W766230837 type Work @default.
- W766230837 sameAs 766230837 @default.
- W766230837 citedByCount "0" @default.
- W766230837 crossrefType "journal-article" @default.
- W766230837 hasAuthorship W766230837A5005936582 @default.
- W766230837 hasAuthorship W766230837A5008690145 @default.
- W766230837 hasAuthorship W766230837A5029792261 @default.
- W766230837 hasAuthorship W766230837A5089698306 @default.
- W766230837 hasConcept C104317684 @default.
- W766230837 hasConcept C137620995 @default.
- W766230837 hasConcept C199835354 @default.
- W766230837 hasConcept C29537977 @default.
- W766230837 hasConcept C30145163 @default.
- W766230837 hasConcept C41008148 @default.
- W766230837 hasConcept C502942594 @default.
- W766230837 hasConcept C54355233 @default.
- W766230837 hasConcept C62478195 @default.
- W766230837 hasConcept C86803240 @default.
- W766230837 hasConcept C95444343 @default.
- W766230837 hasConceptScore W766230837C104317684 @default.
- W766230837 hasConceptScore W766230837C137620995 @default.
- W766230837 hasConceptScore W766230837C199835354 @default.
- W766230837 hasConceptScore W766230837C29537977 @default.
- W766230837 hasConceptScore W766230837C30145163 @default.
- W766230837 hasConceptScore W766230837C41008148 @default.
- W766230837 hasConceptScore W766230837C502942594 @default.
- W766230837 hasConceptScore W766230837C54355233 @default.
- W766230837 hasConceptScore W766230837C62478195 @default.
- W766230837 hasConceptScore W766230837C86803240 @default.
- W766230837 hasConceptScore W766230837C95444343 @default.
- W766230837 hasIssue "3" @default.
- W766230837 hasLocation W7662308371 @default.
- W766230837 hasOpenAccess W766230837 @default.
- W766230837 hasPrimaryLocation W7662308371 @default.
- W766230837 hasVolume "10" @default.
- W766230837 isParatext "false" @default.
- W766230837 isRetracted "false" @default.
- W766230837 magId "766230837" @default.
- W766230837 workType "article" @default.