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- W76684458 abstract "ABSTRACT Toxic effects and deaths in humans due to consumption of nuts or other foods containing amygdalin have been reported by many investigators. The toxicity is due to the release of HCN in gut, upon hydrolysis of amygdalin. Meanwhile similar toxic effects have not been observed in experimental animals. We investigated the effect of intestinal and fecal flora from various species on hydrolytic breakdown of amygdalin. A recently developed gas liquid chromatographic method for quantitation of amygdalin by measuring underivatized benzaldehyde extracted from the anaerobically conducted enzymatic hydrolysis with emulsin, was employed. Samples of feces of mouse, rat, hamster, guinea pig, monkey and man were analyzed for their ability to hydrolyze amygdalin. A great variation was found in the relative potency to hydrolyze amygdalin among different individuals of the same species, but even greater variations were found between different species. These preliminary data suggest that man may be more susceptible to amygdalin poisoning than other tested species. It was also found that some foods possess enzyme(s) which can hydrolyze amygdalin. These data suggest that severe toxic effects could be expected if individuals taking amygdalin (in foods or as tablets) are simultaneously consuming diets containing emulsin or other similar enzymes." @default.
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- W76684458 date "1980-01-01" @default.
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- W76684458 title "ENZYMATIC HYDROLYSIS OF AMYGDALIN BY FECAL SAMPLES AND SOME FOODS" @default.
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- W76684458 doi "https://doi.org/10.1016/b978-0-08-024952-0.50083-1" @default.
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