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- W76703535 abstract "The aim of pathology is to diagnose disease through the study of morphologic alterations in cells and tissues. This can be achieved using two approaches: histopathology and cytopathology. Histopathology is examination of tissues, both macroscopic and microscopic; cytopathology is the study of cells dissociated from their surrounding tissues. Both histopathology and cytopathology are widely use in the diagnosis and prognostication of cancer, to determine the presence and extent of the neoplastic disease, and to assess tumor grading and staging. In most specimens, microscopic diagnosis is accurate; however, selected cases with overlapping morphological features need a further step. This step is represented by ancillary tests: histochemistry, immunohistochemistry, and molecular biology. These techniques, which have changed histopathology significantly, in particular molecular tests, are based on the detection of abnormalities in deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), extracted from accurately selected samples and are at the forefront of diagnostic modern pathology." @default.
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- W76703535 date "2012-01-01" @default.
- W76703535 modified "2023-09-27" @default.
- W76703535 title "Biopsic Sampling (Cancer)" @default.
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- W76703535 doi "https://doi.org/10.1016/b978-0-12-381373-2.00028-4" @default.
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