FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W767756093> ?p ?o ?g. }

• W767756093 abstract "Numerous researchers have studied the relationship between colic and laminitis manifestation. Some studies with experimentally induced laminitis demonstrated involvement of the inflammatory response in the development of the disease. Therefore, the aim of this study was to investigate systemic and local inflammatory response, in intestines and hoof dermal and epidermal tissues, as well as to determine clinical and laboratory changes after intraluminal obstruction in small colon. For this purpose, eight healthy adult horses were submitted to a celiotomy to induce intraluminal distension of the small colon simulating acute abdomen by enterolith. Hoof and small colon biopsies were made at this time, and samples of blood and peritoneal fluid were collected. After four hours of intraluminal obstruction, the ball was deflated and new biopsies of hoof and small colon collected and blood and peritoneal fluid sampled. During the postoperative, animals were monitored by physical examinations every 12 hours. After 72 hours of ball removal, the last biopsies of hoof, colon, blood and peritoneal fluid were collected. The samples of blood and peritoneal fluid were used for hematological evaluation, for determining gene expression of IL1 , IL-6, IL-8, IL-10 and TNFby real-time PCR and to quantify IL-1 , IL6 and TNFby sandwich ELISA. Tissues obtained from biopsies were processed for histological evaluation and determination of IL-1 , IL-6, IL-8, IL10 and TNFby real time PCR. The values obtained in hematological evaluation differ (p<0.05) from baseline, especially four hours after obstruction (M4) and after 12 hours of postoperative (M12). Cytokines concentrations in peritoneal fluid increased in M4, returned to baseline within M72 and remained unchanged in serum samples. Regarding gene expression in blood, there was no significant difference. In peritoneal fluid, all cytokines differed from baseline. Concerning the colon, the TNFdiffered in oral and aboral segments. In the hoof, only TNFwas significant, increasing in M72. Histopathological changes were observed in hoof and colon. These changes were more evident in the segment where the balloon was located during obstruction. The changes found in the hoof dermal and epidermal laminae were described as early changes of laminitis, but no clinical signs were observed during the experimental period." @default.
• W767756093 created "2016-06-24" @default.
• W767756093 creator A5035891155 @default.
• W767756093 date "2014-03-17" @default.
• W767756093 modified "2023-09-23" @default.
• W767756093 title "RESPOSTAS INFLAMATÓRIAS SISTÊMICA, DO CASCO E DO CÓLON MENOR SUBMETIDO À DISTENSÃO EM EQUINOS" @default.
• W767756093 cites W1483162601 @default.
• W767756093 cites W1485234641 @default.
• W767756093 cites W1506296288 @default.
• W767756093 cites W1513532301 @default.
• W767756093 cites W1544719338 @default.
• W767756093 cites W1593136742 @default.
• W767756093 cites W1848628272 @default.
• W767756093 cites W1895694504 @default.
• W767756093 cites W1971306406 @default.
• W767756093 cites W1971845659 @default.
• W767756093 cites W1975286267 @default.
• W767756093 cites W1985178609 @default.
• W767756093 cites W1997023449 @default.
• W767756093 cites W2004213488 @default.
• W767756093 cites W2009621705 @default.
• W767756093 cites W2010220478 @default.
• W767756093 cites W2014000926 @default.
• W767756093 cites W2025363673 @default.
• W767756093 cites W2026769337 @default.
• W767756093 cites W2035637355 @default.
• W767756093 cites W2043114006 @default.
• W767756093 cites W2046783872 @default.
• W767756093 cites W2053497776 @default.
• W767756093 cites W2055922349 @default.
• W767756093 cites W2057484769 @default.
• W767756093 cites W2066215328 @default.
• W767756093 cites W2071419986 @default.
• W767756093 cites W2072056989 @default.
• W767756093 cites W2077831070 @default.
• W767756093 cites W2079586398 @default.
• W767756093 cites W2083841175 @default.
• W767756093 cites W2088220499 @default.
• W767756093 cites W2090246418 @default.
• W767756093 cites W2094205039 @default.
• W767756093 cites W2097744068 @default.
• W767756093 cites W2099787454 @default.
• W767756093 cites W2101509635 @default.
• W767756093 cites W2103835655 @default.
• W767756093 cites W2107979946 @default.
• W767756093 cites W2134363454 @default.
• W767756093 cites W2143521538 @default.
• W767756093 cites W2153416764 @default.
• W767756093 cites W2163496617 @default.
• W767756093 cites W2165337374 @default.
• W767756093 cites W2167693994 @default.
• W767756093 cites W2170868382 @default.
• W767756093 cites W2252444544 @default.
• W767756093 cites W2409504381 @default.
• W767756093 cites W2463911813 @default.
• W767756093 cites W2492330747 @default.
• W767756093 cites W2775092586 @default.
• W767756093 cites W3196870011 @default.
• W767756093 cites W6484673 @default.
• W767756093 cites W802558524 @default.
• W767756093 cites W2074907798 @default.
• W767756093 hasPublicationYear "2014" @default.
• W767756093 type Work @default.
• W767756093 sameAs 767756093 @default.
• W767756093 citedByCount "0" @default.
• W767756093 crossrefType "journal-article" @default.
• W767756093 hasAuthorship W767756093A5035891155 @default.
• W767756093 hasConcept C105702510 @default.
• W767756093 hasConcept C126322002 @default.
• W767756093 hasConcept C141071460 @default.
• W767756093 hasConcept C142724271 @default.
• W767756093 hasConcept C2776625112 @default.
• W767756093 hasConcept C2777652987 @default.
• W767756093 hasConcept C2779983558 @default.
• W767756093 hasConcept C71924100 @default.
• W767756093 hasConcept C90924648 @default.
• W767756093 hasConcept C98055416 @default.
• W767756093 hasConceptScore W767756093C105702510 @default.
• W767756093 hasConceptScore W767756093C126322002 @default.
• W767756093 hasConceptScore W767756093C141071460 @default.
• W767756093 hasConceptScore W767756093C142724271 @default.
• W767756093 hasConceptScore W767756093C2776625112 @default.
• W767756093 hasConceptScore W767756093C2777652987 @default.
• W767756093 hasConceptScore W767756093C2779983558 @default.
• W767756093 hasConceptScore W767756093C71924100 @default.
• W767756093 hasConceptScore W767756093C90924648 @default.
• W767756093 hasConceptScore W767756093C98055416 @default.
• W767756093 hasLocation W7677560931 @default.
• W767756093 hasOpenAccess W767756093 @default.
• W767756093 hasPrimaryLocation W7677560931 @default.
• W767756093 isParatext "false" @default.
• W767756093 isRetracted "false" @default.
• W767756093 magId "767756093" @default.
• W767756093 workType "article" @default.