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- W76778876 abstract "Activated microglia release a number of substances, the specific cocktail released depending on the stimulus. Many of the substances released by microglia also serve to activate them, suggesting the presence of a number of autocrine/paracrine loops. Because of the low density of microglia present in the normal brain, such autocrine/paracrine loops may not be significant but during the initiation and ongoing states of neurodegeneration, the increased concentrations of microglia may allow the activation and escalated stimulation of these feedback pathways. The activation of p38 MAPK by A beta and cytokines may be part of a microglial autocrine loop which results in the fueling of the microglial inflammatory response. A novel class of cytokine suppressive anti-inflammatory drugs (CSAIDs) inhibit the activation of p38 kinase (Bhat et al., 1998) suggesting this kinase plays a key role in transducing microglial responses to activation stimuli (Badger et al., 1996)." @default.
- W76778876 created "2016-06-24" @default.
- W76778876 creator A5042759254 @default.
- W76778876 creator A5068969195 @default.
- W76778876 date "2001-01-01" @default.
- W76778876 modified "2023-09-27" @default.
- W76778876 title "Microglial signalling cascades in neurodegenerative disease" @default.
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- W76778876 cites W1916393557 @default.
- W76778876 cites W1937157394 @default.
- W76778876 cites W1965149830 @default.
- W76778876 cites W1965828887 @default.
- W76778876 cites W1965878134 @default.
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- W76778876 cites W1971313633 @default.
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- W76778876 doi "https://doi.org/10.1016/s0079-6123(01)32103-9" @default.
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