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• W76804593 abstract "textabstractThe purpose of this study was to improve the diagnosis of human malignantmesothelioma on the one hand and to investigate the growth regulation andtransformation of normal and malignant mesothelial cells on the other hand.In this thesis improvement of diagnosis was approached by the search forspecific tumor markers. Therefore malignant mesotheliomas were analysed for theirchromosomal aberrations and the expression of specific membrane antigen markers.For the investigation of the growth regulation in normal and malignant mesothelial cellsa panel of in vitro growing malignant mesothelioma cell lines was established. Thesecell lines were studied for expression of growth factors and their receptors, with emphasis on the platelet-derived growth factor and its receptor. Evidence has beenobtained that platelet-derived growth factor (PDGF) may play a role in the malignanttransformation of mesothelial cells." @default.
• W76804593 created "2016-06-24" @default.
• W76804593 creator A5006234724 @default.
• W76804593 date "1989-11-22" @default.
• W76804593 modified "2023-09-26" @default.
• W76804593 title "Malignant mesothelioma, clinical, diagnostic and cell biological investigations" @default.
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• W76804593 hasPublicationYear "1989" @default.
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