FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W768322440> ?p ?o ?g. }

• W768322440 endingPage "536" @default.
• W768322440 startingPage "533" @default.
• W768322440 abstract "Juvenile systemic lupus erythematosus (JSLE) is a multi-system autoimmune disorder of unknown origin. Given the importance of the contribution of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α), towards the pathogenesis of JSLE, this study was performed to assess TNFA gene polymorphisms in a case-control study. Fifty nine patients with JSLE were enrolled in this study as case group and compared with healthy control subjects. The frequency of alleles, genotypes, and haplotypes of TNFA single-nucleotide polymorphisms (SNPs) at positions −308 and −238 were evaluated, using polymerase chain reaction with sequence-specific primers method. The G allele at position −238 in TNFA promoter region was significantly more frequent in patients with JSLE than in the healthy controls (P value < 0.001), while the frequency of A allele at the same position was significantly lower than controls. Furthermore, a significant positive association for G/G genotype at the same position was detected in patients’ group compared with control subjects (P value < 0.001). The GA haplotype of TNFA (positions −308, −238) was significantly less frequent in case group than in controls (P value < 0.001), while GG was the most frequent haplotype for TNFA in the patient group, compared to controls (P value < 0.01). Pro-inflammatory cytokine gene polymorphisms may influence susceptibility to JSLE. Particular TNFA gene variants are associated with JSLE and could be used as a genetic marker for susceptibility to JSLE." @default.
• W768322440 created "2016-06-24" @default.
• W768322440 creator A5028354492 @default.
• W768322440 creator A5028472220 @default.
• W768322440 creator A5030951670 @default.
• W768322440 creator A5034075627 @default.
• W768322440 creator A5045214596 @default.
• W768322440 creator A5056899761 @default.
• W768322440 creator A5060184273 @default.
• W768322440 creator A5068062751 @default.
• W768322440 creator A5080185559 @default.
• W768322440 creator A5090319212 @default.
• W768322440 date "2015-08-01" @default.
• W768322440 modified "2023-09-28" @default.
• W768322440 title "Tumor necrosis factor-alpha single nucleotide polymorphisms in juvenile systemic lupus erythematosus" @default.
• W768322440 cites W1510756896 @default.
• W768322440 cites W1606884952 @default.
• W768322440 cites W1819074277 @default.
• W768322440 cites W1967908665 @default.
• W768322440 cites W1975616423 @default.
• W768322440 cites W1986515052 @default.
• W768322440 cites W1991060602 @default.
• W768322440 cites W1997773350 @default.
• W768322440 cites W2008062171 @default.
• W768322440 cites W2009008398 @default.
• W768322440 cites W2014916760 @default.
• W768322440 cites W2016954412 @default.
• W768322440 cites W2017822310 @default.
• W768322440 cites W2020619427 @default.
• W768322440 cites W2023376381 @default.
• W768322440 cites W2028156913 @default.
• W768322440 cites W2031357644 @default.
• W768322440 cites W2034657358 @default.
• W768322440 cites W2037398709 @default.
• W768322440 cites W2040117090 @default.
• W768322440 cites W2046012831 @default.
• W768322440 cites W2046973175 @default.
• W768322440 cites W2062049452 @default.
• W768322440 cites W2063834123 @default.
• W768322440 cites W2070527591 @default.
• W768322440 cites W2072681359 @default.
• W768322440 cites W2083847672 @default.
• W768322440 cites W2087785715 @default.
• W768322440 cites W2091842850 @default.
• W768322440 cites W2093109764 @default.
• W768322440 cites W2108529019 @default.
• W768322440 cites W2113774205 @default.
• W768322440 cites W2118094114 @default.
• W768322440 cites W2121171258 @default.
• W768322440 cites W2126352920 @default.
• W768322440 cites W2129202470 @default.
• W768322440 cites W2129889907 @default.
• W768322440 cites W2130669297 @default.
• W768322440 cites W2133422071 @default.
• W768322440 cites W2150882333 @default.
• W768322440 cites W2164197115 @default.
• W768322440 cites W2169832373 @default.
• W768322440 cites W2316898267 @default.
• W768322440 cites W2335610221 @default.
• W768322440 doi "https://doi.org/10.1016/j.humimm.2015.06.011" @default.
• W768322440 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26116096" @default.
• W768322440 hasPublicationYear "2015" @default.
• W768322440 type Work @default.
• W768322440 sameAs 768322440 @default.
• W768322440 citedByCount "17" @default.
• W768322440 countsByYear W7683224402016 @default.
• W768322440 countsByYear W7683224402017 @default.
• W768322440 countsByYear W7683224402018 @default.
• W768322440 countsByYear W7683224402019 @default.
• W768322440 countsByYear W7683224402020 @default.
• W768322440 countsByYear W7683224402023 @default.
• W768322440 crossrefType "journal-article" @default.
• W768322440 hasAuthorship W768322440A5028354492 @default.
• W768322440 hasAuthorship W768322440A5028472220 @default.
• W768322440 hasAuthorship W768322440A5030951670 @default.
• W768322440 hasAuthorship W768322440A5034075627 @default.
• W768322440 hasAuthorship W768322440A5045214596 @default.
• W768322440 hasAuthorship W768322440A5056899761 @default.
• W768322440 hasAuthorship W768322440A5060184273 @default.
• W768322440 hasAuthorship W768322440A5068062751 @default.
• W768322440 hasAuthorship W768322440A5080185559 @default.
• W768322440 hasAuthorship W768322440A5090319212 @default.
• W768322440 hasConcept C104317684 @default.
• W768322440 hasConcept C126322002 @default.
• W768322440 hasConcept C135763542 @default.
• W768322440 hasConcept C146304588 @default.
• W768322440 hasConcept C153209595 @default.
• W768322440 hasConcept C17991360 @default.
• W768322440 hasConcept C180754005 @default.
• W768322440 hasConcept C197754878 @default.
• W768322440 hasConcept C203014093 @default.
• W768322440 hasConcept C2780942790 @default.
• W768322440 hasConcept C37463918 @default.
• W768322440 hasConcept C54355233 @default.
• W768322440 hasConcept C71924100 @default.
• W768322440 hasConcept C86803240 @default.
• W768322440 hasConceptScore W768322440C104317684 @default.
• W768322440 hasConceptScore W768322440C126322002 @default.

• next