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- W768331379 abstract "Regular and modified CPP were synthesized in solid phase by general Fmoc synthesis strategy on Wang resin. Coupling of fluorescein isothiocyanate (FITC) and gadolinium (Gd) chelator DOTA (trist-Bu-ester) was done on resin as well [1, 2]. In case of stearoyl modified CA [3] an additional lysine was introduced between the peptide and Gd chelator to link the fatty acid residue. CA were cleaved from resin and loaded with Gd in water. Compounds were purified by RP-HPLC, freeze-dried and analyzed by ESI-MS. 1Max Planck Institute for Biological Cybernetics, Tubingen, Germany. 2EMC microcollections GmbH, Tubingen 3Institute of Organic Chemistry, University of Tubingen.,4Siemens Medical Solutions, MREA Neuro, Erlangen, Germany,5Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, US" @default.
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- W768331379 date "2007-03-01" @default.
- W768331379 modified "2023-10-12" @default.
- W768331379 title "Cell Penetrating Peptides and their conjugates for optical and MR imaging techniques" @default.
- W768331379 hasPublicationYear "2007" @default.
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