Matches in SemOpenAlex for { <https://semopenalex.org/work/W76957218> ?p ?o ?g. }
- W76957218 abstract "ABSTRACT Commercial chlorinated and brominated biphenyls are mixtures of many isomers. They may be contaminated by halogenated naphthalenes and dibenzofurans. Diseases caused by these compounds include chloracne and liver disease in humans, hyperkeratosis or x-disease in cattle, and chickedema in chickens. In rodents, the halogenated biphenyls primarily affect the liver. In female rats, hepatic porphyria is easily produced, and in males, lipids accumulate in the liver. Liver tumors, including carcinomas, have been produced with chlorinated biphenyls in rats and mice. It is possible to produce hepatocellular carcinomas in rats with a single, high, oral dose of polybrominated biphenyls (1,000 mg/kg b.w.) given early in life. It is not yet clear whether specific isomers cause most of the toxic effects in animals and men. It is, therefore, difficult to predict what the long-term health effects would be from exposure to mixtures that have not been well characterized." @default.
- W76957218 created "2016-06-24" @default.
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- W76957218 date "1981-01-01" @default.
- W76957218 modified "2023-09-25" @default.
- W76957218 title "CHRONIC TOXICITY OF HALOGENATED BIPHENYLS AND RELATED COMPOUNDS IN ANIMALS AND HEALTH EFFECTS IN HUMANS" @default.
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- W76957218 doi "https://doi.org/10.1016/b978-0-08-027530-7.50008-x" @default.
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