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• W770280690 abstract "Development and Use of a Physiologically-based Mathematical Model Describing the Relationships and Contributions of Macronutrients to Weight and Body Composition Changes Saori Sakita Department of Nutrition, Dietetics, and Food Science Master of Nutritional Science The effect of the dietary macronutrient composition on weight loss has been a controversial issue for decades. During that time, a high-protein, high-fat, and lowcarbohydrate diet has been one of the more popular weight loss diets with the public. We hypothesized that a computer simulation model using STELLA software could help to better understanding the effect of the dietary macronutrient composition on weight loss. We calculated daily total oxidation instead of total energy expenditure as others have done based on the facts that carbohydrate, fat, and protein intake influence carbohydrate, fat, and protein oxidation. In order to create a simple and accurate model comparing dietary macronutrient composition effects, we eliminated exercise as a factor and focused on a sedentary population. The model was validated by five sets of published human data. Following model validation, simulations were carried out to compare the traditional highcarbohydrate diet recommended by the American Dietetic Association and two wellknown high-protein diets (Atkins and the Zone diet). The results of computer simulation suggested that the lean tissue retention effect of a high-protein diet, especially with a lower-fat diet, compared with a traditional high carbohydrate diet over 6 months." @default.
• W770280690 created "2016-06-24" @default.
• W770280690 creator A5030647691 @default.
• W770280690 date "2010-01-01" @default.
• W770280690 modified "2023-09-26" @default.
• W770280690 title "Development and Use of a Physiologically Based Mathematical Model Describing the Relationships and Contributions of Macronutrients to Weight and Body Composition Changes" @default.
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• W770280690 hasPublicationYear "2010" @default.
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