FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W77052274> ?p ?o ?g. }

• W77052274 endingPage "72" @default.
• W77052274 startingPage "45" @default.
• W77052274 abstract "The multifactorial etiology of hypospadias is becoming more clearly defined with ongoing investigation. Endogenous endocrine abnormalities identified so far include testosterone biosynthesis defects, 5alpha-reductase type 2 mutations, and androgen receptor mutations (the rarest cause, even in cases of severe hypospadias). Other significant risk factors include IVF (because of progesterone administration or endocrine abnormalities associated with infertility) and environmental agents that can potentially cause testicular dysgenesis, disrupt the male androgen axis, and disturb normal male genital embryology (Table 6). [table; see text] It also seems that the incidence of hypospadias is increasing, both in the United States and in Europe--which may be due to better medical care for those with genital abnormalities and/or infertility problems, as well as environmental endocrine disruptors. Hypospadias is a physical manifestation that may be a consequence of numerous physiological aberrations, and our ability to understand and to potentially prevent this congenital malformation will require a significant amount of additional work. Our challenge for the future remains to identify the various etiologies, provide prenatal counseling for affected families with a history of hypospadias, and minimize or eliminate exposure to environmental agents that may contribute to this problem. Perhaps one day we will be able to offer prenatal therapy to prevent hypospadias when the risk for this birth defect seems high. How might this be possible? Consider the modern management of a family with a child born with the adrenogenital syndrome, another endocrine derangement that can cause abnormal genital development. In this situation, dexamethasone can be administered to the mother in subsequent pregnancies to prevent fetal virilization until the sex of the fetus can be determined or adrenal enzyme mutations can be excluded. Perhaps in the future a similar approach will be taken for those families with strong risk factors for hypospadias." @default.
• W77052274 created "2016-06-24" @default.
• W77052274 creator A5010622314 @default.
• W77052274 date "2004-01-01" @default.
• W77052274 modified "2023-10-15" @default.
• W77052274 title "Endocrine Abnormalities in Boys with Hypospadias" @default.
• W77052274 cites W1502119727 @default.
• W77052274 cites W1951037239 @default.
• W77052274 cites W1964079425 @default.
• W77052274 cites W1965055474 @default.
• W77052274 cites W1966826515 @default.
• W77052274 cites W1968824285 @default.
• W77052274 cites W1971069843 @default.
• W77052274 cites W1977711494 @default.
• W77052274 cites W1979882845 @default.
• W77052274 cites W1980083702 @default.
• W77052274 cites W1980967604 @default.
• W77052274 cites W1984483201 @default.
• W77052274 cites W1988347230 @default.
• W77052274 cites W1991371888 @default.
• W77052274 cites W1998761029 @default.
• W77052274 cites W1999330754 @default.
• W77052274 cites W2000011814 @default.
• W77052274 cites W2012607667 @default.
• W77052274 cites W2013922358 @default.
• W77052274 cites W2015453176 @default.
• W77052274 cites W2017900385 @default.
• W77052274 cites W2019289610 @default.
• W77052274 cites W2021847319 @default.
• W77052274 cites W2025048879 @default.
• W77052274 cites W2026515198 @default.
• W77052274 cites W2026593665 @default.
• W77052274 cites W2032123774 @default.
• W77052274 cites W2032757820 @default.
• W77052274 cites W2043288899 @default.
• W77052274 cites W2050044266 @default.
• W77052274 cites W2051924364 @default.
• W77052274 cites W2055021839 @default.
• W77052274 cites W2059121174 @default.
• W77052274 cites W2064654876 @default.
• W77052274 cites W2070285276 @default.
• W77052274 cites W2070886736 @default.
• W77052274 cites W2072466171 @default.
• W77052274 cites W2077750390 @default.
• W77052274 cites W2080166321 @default.
• W77052274 cites W2081251422 @default.
• W77052274 cites W2088491872 @default.
• W77052274 cites W2092410857 @default.
• W77052274 cites W2100283471 @default.
• W77052274 cites W2107006066 @default.
• W77052274 cites W2108304881 @default.
• W77052274 cites W2109218990 @default.
• W77052274 cites W2114029582 @default.
• W77052274 cites W2121284503 @default.
• W77052274 cites W2122869929 @default.
• W77052274 cites W2131218665 @default.
• W77052274 cites W2135747955 @default.
• W77052274 cites W2144032971 @default.
• W77052274 cites W2148427114 @default.
• W77052274 cites W2152406817 @default.
• W77052274 cites W2171423639 @default.
• W77052274 cites W2237018815 @default.
• W77052274 cites W2287877674 @default.
• W77052274 cites W2325166427 @default.
• W77052274 cites W2332202164 @default.
• W77052274 cites W2408385251 @default.
• W77052274 cites W2414585847 @default.
• W77052274 cites W2414846540 @default.
• W77052274 cites W2415539309 @default.
• W77052274 cites W2418568951 @default.
• W77052274 cites W2437073075 @default.
• W77052274 cites W32684353 @default.
• W77052274 cites W4234786685 @default.
• W77052274 cites W4237673485 @default.
• W77052274 cites W4240426387 @default.
• W77052274 cites W4242633748 @default.
• W77052274 cites W4244553337 @default.
• W77052274 cites W4247893536 @default.
• W77052274 doi "https://doi.org/10.1007/978-1-4419-8995-6_4" @default.
• W77052274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15086020" @default.
• W77052274 hasPublicationYear "2004" @default.
• W77052274 type Work @default.
• W77052274 sameAs 77052274 @default.
• W77052274 citedByCount "24" @default.
• W77052274 countsByYear W770522742012 @default.
• W77052274 countsByYear W770522742014 @default.
• W77052274 countsByYear W770522742015 @default.
• W77052274 countsByYear W770522742017 @default.
• W77052274 countsByYear W770522742021 @default.
• W77052274 countsByYear W770522742022 @default.
• W77052274 crossrefType "book-chapter" @default.
• W77052274 hasAuthorship W77052274A5010622314 @default.
• W77052274 hasConcept C126322002 @default.
• W77052274 hasConcept C134018914 @default.
• W77052274 hasConcept C137627325 @default.
• W77052274 hasConcept C141071460 @default.
• W77052274 hasConcept C183021626 @default.
• W77052274 hasConcept C187212893 @default.

• next