FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W770590952> ?p ?o ?g. }

• W770590952 abstract "Japanese encephalitis virus (JEV) is an important zoonotic pathogen causing viral encephalitis in human and reproductive failure in pigs. In the present study, we first examined the autophagy induced by JEV infection in host cells, and then analyzed the JEV proteins involving in autophagy induction, and further investigated the relationship between viral protein and immunity-related GTPases M (IRGM). Our results showed that JEV infection could induce autophagy in host cells and autophagy promoted the replication of JEV in vitro; the cells transfected with individual plasmid that was expressing C, M and NS3 had a significantly higher conversion of LC3-I/II, and enhanced LC3 signals with the fluorescence punctuates accumulation which was completely co-localized with LC3 and increased number of autophagosomes-like vesicles, suggesting that C, M and NS3 are the major viral proteins involving in autophagy induction upon JEV infection; the virus titer in the cells treated by the siRNA specific for IRGM had a significant decrease, and the NS3 signals in the cells transfected with the plasmid that was expressing NS3 were completely co-localized with the IRGM signals, suggesting that the NS3 of JEV could target IRGM which may play a role in the replication of JEV. Our findings help to understand the role of autophagy in JEV and other flaviviruses infections." @default.
• W770590952 created "2016-06-24" @default.
• W770590952 creator A5012443625 @default.
• W770590952 creator A5040826353 @default.
• W770590952 creator A5045366427 @default.
• W770590952 creator A5048277748 @default.
• W770590952 creator A5049445988 @default.
• W770590952 creator A5050388216 @default.
• W770590952 creator A5085081570 @default.
• W770590952 date "2015-08-01" @default.
• W770590952 modified "2023-09-30" @default.
• W770590952 title "Capsid, membrane and NS3 are the major viral proteins involved in autophagy induced by Japanese encephalitis virus" @default.
• W770590952 cites W126188432 @default.
• W770590952 cites W1857967627 @default.
• W770590952 cites W1965603799 @default.
• W770590952 cites W1968652010 @default.
• W770590952 cites W1975050610 @default.
• W770590952 cites W1988796772 @default.
• W770590952 cites W2004704734 @default.
• W770590952 cites W2012612576 @default.
• W770590952 cites W2014366923 @default.
• W770590952 cites W2018580504 @default.
• W770590952 cites W2019878519 @default.
• W770590952 cites W2020914318 @default.
• W770590952 cites W2022971229 @default.
• W770590952 cites W2025364264 @default.
• W770590952 cites W2025988707 @default.
• W770590952 cites W2034872680 @default.
• W770590952 cites W2037563133 @default.
• W770590952 cites W2042260827 @default.
• W770590952 cites W2046388378 @default.
• W770590952 cites W2053581512 @default.
• W770590952 cites W2059346225 @default.
• W770590952 cites W2063323349 @default.
• W770590952 cites W2065748927 @default.
• W770590952 cites W2074188269 @default.
• W770590952 cites W2079046408 @default.
• W770590952 cites W2081057817 @default.
• W770590952 cites W2083577204 @default.
• W770590952 cites W2096308078 @default.
• W770590952 cites W2099616958 @default.
• W770590952 cites W2106409322 @default.
• W770590952 cites W2109559593 @default.
• W770590952 cites W2123102587 @default.
• W770590952 cites W2131997549 @default.
• W770590952 cites W2134407906 @default.
• W770590952 cites W2135574023 @default.
• W770590952 cites W2145265436 @default.
• W770590952 cites W2149590832 @default.
• W770590952 cites W2163412375 @default.
• W770590952 doi "https://doi.org/10.1016/j.vetmic.2015.05.026" @default.
• W770590952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26043943" @default.
• W770590952 hasPublicationYear "2015" @default.
• W770590952 type Work @default.
• W770590952 sameAs 770590952 @default.
• W770590952 citedByCount "14" @default.
• W770590952 countsByYear W7705909522016 @default.
• W770590952 countsByYear W7705909522017 @default.
• W770590952 countsByYear W7705909522018 @default.
• W770590952 countsByYear W7705909522019 @default.
• W770590952 countsByYear W7705909522020 @default.
• W770590952 countsByYear W7705909522021 @default.
• W770590952 countsByYear W7705909522022 @default.
• W770590952 countsByYear W7705909522023 @default.
• W770590952 crossrefType "journal-article" @default.
• W770590952 hasAuthorship W770590952A5012443625 @default.
• W770590952 hasAuthorship W770590952A5040826353 @default.
• W770590952 hasAuthorship W770590952A5045366427 @default.
• W770590952 hasAuthorship W770590952A5048277748 @default.
• W770590952 hasAuthorship W770590952A5049445988 @default.
• W770590952 hasAuthorship W770590952A5050388216 @default.
• W770590952 hasAuthorship W770590952A5085081570 @default.
• W770590952 hasConcept C132379496 @default.
• W770590952 hasConcept C140704245 @default.
• W770590952 hasConcept C159047783 @default.
• W770590952 hasConcept C190283241 @default.
• W770590952 hasConcept C202878990 @default.
• W770590952 hasConcept C203522944 @default.
• W770590952 hasConcept C2522874641 @default.
• W770590952 hasConcept C2776408679 @default.
• W770590952 hasConcept C2779141303 @default.
• W770590952 hasConcept C2779734145 @default.
• W770590952 hasConcept C2780568436 @default.
• W770590952 hasConcept C54009773 @default.
• W770590952 hasConcept C54355233 @default.
• W770590952 hasConcept C55493867 @default.
• W770590952 hasConcept C81885089 @default.
• W770590952 hasConcept C83455156 @default.
• W770590952 hasConcept C86803240 @default.
• W770590952 hasConceptScore W770590952C132379496 @default.
• W770590952 hasConceptScore W770590952C140704245 @default.
• W770590952 hasConceptScore W770590952C159047783 @default.
• W770590952 hasConceptScore W770590952C190283241 @default.
• W770590952 hasConceptScore W770590952C202878990 @default.
• W770590952 hasConceptScore W770590952C203522944 @default.
• W770590952 hasConceptScore W770590952C2522874641 @default.
• W770590952 hasConceptScore W770590952C2776408679 @default.
• W770590952 hasConceptScore W770590952C2779141303 @default.
• W770590952 hasConceptScore W770590952C2779734145 @default.
• W770590952 hasConceptScore W770590952C2780568436 @default.

• next